FLORENCE, Italy & BARCELONA, Spain--(BUSINESS WIRE)--Dec 11, 2024-- The Menarini Group ("Menarini"), a leading international pharmaceutical and diagnostics company, and Stemline Therapeutics, Inc. ("Stemline"), a wholly-owned subsidiary of the Menarini Group focused on bringing transformational oncology treatments to cancer patients, along with MEDSIR, a leading global independent clinical research company in oncology and part of Oncoclínicas & Co., the largest specialized oncology treatment group in Latin America, presented research on the pioneering clinical trial ADELA. This important research addresses therapeutic resistance in advanced ER+/HER2- breast cancer. Presented at the San Antonio Breast Cancer Symposium 2024 (SABCS), the study represents a key milestone in the quest for more effective and personalized treatment options for patients with disease progression. The standard first-line treatment for advanced ER+/HER2- breast cancer combines endocrine therapy with CDK4/6 inhibitors. ESR1 mutations develop as a result of prior exposure to endocrine therapy during metastatic treatment, and up to 50% of ER+, HER2- advanced or metastatic breast cancers will develop these mutations. ESR1 mutations cause the tumors to become resistant to endocrine therapy, in turn causing the cancer to progress; therefore, it is important to test for ESR1 whenever mBC progresses. Longer exposure to endocrine therapy during first-line treatment increases the chance of a patient’s tumor developing an ESR1 mutation. With the goal of addressing this unmet medical need, the ADELA phase III clinical trial investigates a new therapeutic option combining elacestrant, a next generation, oral selective estrogen receptor degrader, with everolimus, an mTORC1 inhibitor. This combination is being evaluated in patients with advanced ER+/HER2- breast cancer that harbors ESR1 mutations, and who have experienced progression after standard first-line treatment. Results from the phase III EMERALD study were the basis for elacestrant’s approval. Meanwhile, everolimus has shown efficacy in inhibiting other resistance mechanisms in this type of cancer. The elacestrant and everolimus combination has demonstrated preliminary efficacy with a manageable safety profile in the phase 1b/2 ELEVATE study ( NCT05563220 ). “We at Menarini Stemline are delighted to announce the collaboration with MEDSIR to continue advancing the clinical research to explore the combination therapy with elacestrant,” said Nassir Habboubi, MD, Chief Medical Officer of Stemline Therapeutics. “We are committed to driving innovation in cancer treatment by delivering transformational therapies aiming to extend the lives of people living with cancer.” The primary objective of this international, randomized, double-blind trial is to evaluate whether the combination of elacestrant and everolimus offers greater efficacy in delaying disease progression compared to elacestrant monotherapy. Additionally, it investigates other crucial aspects, such as overall survival, toxicity profile, and the impact on patients’ quality of life. The ADELA study represents a critical step in understanding how to overcome tumor resistance challenges in patients with ESR1 mutations, with the goal of advancing towards more effective and safer treatments. “At MEDSIR, we understand innovation not only as achieving clinical results but as the ability to transform patients' lives on a global scale. With ADELA, we take a decisive step toward accomplishing less invasive and more accessible treatments, aiming to offer new hope to those facing the most complex forms of the disease. This advancement reinforces our commitment to increasingly personalized and patient-centered medicine, a fundamental pillar in shaping the future of oncology,” said Dr. Antonio Llombart-Cussac, Senior Scientific Leader at MEDSIR. The phase III study not only has significant clinical objectives, but also holds the potential to pave the way for regulatory approval of this therapeutic combination, enabling its use in a broader population of patients with advanced breast cancer. Moreover, the international scope of the study, which includes participation from multiple countries, including Spain, Italy, France, Austria, the Czech Republic, Greece, Germany, and the United Kingdom, underscores the study’s global importance and relevance in the scientific community. The presentation of the ADELA study at an event as prominent as SABCS 2024 reinforces MEDSIR’s leadership in excellence-driven oncology research and highlights its focus on addressing unmet needs in breast cancer treatment. The ADELA study is active and already recruiting patients. About ORSERDU (elacestrant) U.S. Indication: ORSERDU (elacestrant), 345 mg tablets, is indicated for the treatment of postmenopausal women or adult men with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1 -mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy. Full prescribing information for the U.S. can be found at www.orserdu.com . Important Safety Information Warning and Precautions Dyslipidemia : Hypercholesterolemia and hypertriglyceridemia occurred in patients taking ORSERDU at an incidence of 30% and 27%, respectively. The incidence of Grade 3 and 4 hypercholesterolemia and hypertriglyceridemia were 0.9% and 2.2%, respectively. Monitor lipid profile prior to starting and periodically while taking ORSERDU. Embryo-Fetal Toxicity : Based on findings in animals and its mechanism of action, ORSERDU can cause fetal harm when administered to a pregnant woman. Advise pregnant women and females of reproductive potential of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment with ORSERDU and for 1 week after the last dose. Advise male patients with female partners of reproductive potential to use effective contraception during treatment with ORSERDU and for 1 week after the final dose. Adverse Reactions Serious adverse reactions occurred in 12% of patients who received ORSERDU. Serious adverse reactions in >1% of patients who received ORSERDU were musculoskeletal pain (1.7%) and nausea (1.3%). Fatal adverse reactions occurred in 1.7% of patients who received ORSERDU, including cardiac arrest, septic shock, diverticulitis, and unknown cause (one patient each). The most common adverse reactions (≥10%) , including laboratory abnormalities, of ORSERDU were musculoskeletal pain (41%), nausea (35%), increased cholesterol (30%), increased AST (29%), increased triglycerides (27%), fatigue (26%), decreased hemoglobin (26%), vomiting (19%), increased ALT (17%), decreased sodium (16%), increased creatinine (16%), decreased appetite(15%), diarrhea(13%), headache (12%), constipation (12%), abdominal pain (11%), hot flush (11%), and dyspepsia (10%). Drug interactions Concomitant use with CYP3A4 Inducers and/or inhibitors : Avoid concomitant use of strong or moderate CYP3A4 inhibitors with ORSERDU. Avoid concomitant use of strong or moderate CYP3A4 inducers with ORSERDU. Use in specific populations Lactation : Advise lactating women to not breastfeed during treatment with ORSERDU and for 1 week after the last dose. Hepatic Impairment : Avoid use of ORSERDU in patients with severe hepatic impairment (Child-Pugh C). Reduce the dose of ORSERDU in patients with moderate hepatic impairment (Child-Pugh B). The safety and effectiveness of ORSERDU in pediatric patients have not been established. To report SUSPECTED ADVERSE REACTIONS, contact Stemline Therapeutics, Inc. at 1-877-332-7961 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch . About The Menarini Group The Menarini Group is a leading international pharmaceutical and diagnostics company, with a turnover of $4.7 billion and over 17,000 employees. Menarini is focused on therapeutic areas with high unmet needs with products for cardiology, oncology, pneumology, gastroenterology, infectious diseases, diabetology, inflammation, and analgesia. With 18 production sites and 9 Research and Development centers, Menarini’s products are available in 140 countries worldwide. For further information, please visit www.menarini.com . About Stemline Therapeutics Inc. Stemline Therapeutics, Inc. (“Stemline”) a wholly-owned subsidiary of the Menarini Group, is a commercial-stage biopharmaceutical company focused on the development and commercialization of novel oncology therapeutics. Stemline commercializes ORSERDU ® (elacestrant) in the U.S. and Europe, an oral endocrine therapy indicated for the treatment of postmenopausal women or adult men with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy. Stemline also commercializes ELZONRIS ® (tagraxofusp-erzs), a novel targeted treatment directed to CD123 for patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), an aggressive hematologic cancer, in the United States and Europe, which is the only approved treatment for BPDCN in the U.S. and E.U. to date. Stemline also commercializes NEXPOVIO ® (selinexor) in Europe, an XPO1 inhibitor for multiple myeloma. Stemline also has an extensive clinical pipeline of small molecules and biologics in various stages of development for a host of solid and hematologic cancers. About MEDSIR Established in 2012, MEDSIR prides itself on working closely with its strategic partners to drive innovation in oncology research. Operating in Spain and the United States, the company provides end-to-end clinical trial management, from study design to publication, with an extensive global network of experts and integrated technology to streamline the process. The company offers proof-of-concept support and a strategic approach that enables research partners to benefit from the best of both worlds: industry clinical research and investigator-driven trials. With the aim of promoting independent research worldwide, MEDSIR has formed a strategic alliance with Oncoclínicas, the leading oncology group in Brazil, which offers outstanding research potential in South America. For further information: www.medsir.org About Oncoclínicas & CO Oncoclínicas&Co is the largest group dedicated to cancer treatment in Latin America, with a specialized and innovative model focused on the entire oncology care journey, combining operational efficiency, humanized care, and high specialization through a medical team composed of over 2,700 specialist physicians with an emphasis on oncology. With its mission to democratize cancer treatment, it offers a comprehensive system that integrates outpatient clinics with high-complexity cancer centers. The company operates 145 units across 39 Brazilian cities, allowing high-quality access in all regions it serves, aligned with world-class standards. Focusing on technology, precision medicine, and genomics, Oncoclínicas performed approximately 635,000 treatments in 2023. It is the exclusive partner in Brazil of the Dana Farber Cancer Institute, affiliated with Harvard Medical School, one of the world’s leading cancer research and treatments centers. The company also owns Boston Lighthouse Innovation, a bioinformatics firm based in Cambridge, United States, and holds shares in Medsir, a company dedicated to the development and management of clinical trials for independent cancer research, based in Barcelona, Spain. Recently, Oncoclínicas expanded its operations to Saudi Arabia through a joint venture with the Al Faisaliah Group, bringing its mission to beat cancer to a new continent and providing advanced oncology care on a global scale by combining oncological hyperspecialization with innovative treatment approaches. The company is part of the IDIVERSA index, launched by B3, highlighting companies committed to gender and racial diversity. For more information, visit: www.grupooncoclinicas.com . View source version on businesswire.com : https://www.businesswire.com/news/home/20241211008868/en/ CONTACT: Media Contacts The Menarini Group Valeria Speroni Cardi Email:pressoffice@menarini.comStemline Therapeutics, Inc. Cheya Pope Email:media@menarinistemline.comGlobal Brand Communication MEDSIR: Sergio Aguilar Global Brand & Communication Director +34 674 82 87 24 sergio.aguilar@medsir.orgEduardo Martín Espallargas Global Communication & Marketing Manager +34 634 835 389 Eduardo.martin@medsir.orgCarles Berloso Cortés International PR & Comms +34 677 49 75 23 carles.berloso@medsir.org KEYWORD: TEXAS SPAIN NORTH AMERICA UNITED STATES EUROPE ITALY INDUSTRY KEYWORD: RESEARCH CLINICAL TRIALS BIOTECHNOLOGY HEALTH PHARMACEUTICAL GENERAL HEALTH OTHER SCIENCE SCIENCE ONCOLOGY SOURCE: The Menarini Group Copyright Business Wire 2024. PUB: 12/11/2024 06:35 PM/DISC: 12/11/2024 06:35 PM http://www.businesswire.com/news/home/20241211008868/enWashington's to walk out of the Intermediate-Range Nuclear Forces Treaty with Moscow has come back to haunt them, with Russia the Oreshnik (lit. Hazel) - a new hypersonic, medium-range ballistic missile with MIRV capability and the ability to accelerate to speeds up to Mach 10 (over 3 km per second) this week as the US continues the its long-awaited and medium-range missile designs. The development also bears some resemblance to the US's 2002 the Anti-Ballistic Missile Treaty with Russia - which prompted Moscow to work on, , an array of new ballistic and glide hypersonic technologies in the late 2010s, among them the Kinzhal, Avangard and Zircon. Like these earlier systems, the Oreshnik hypersonic ballistic missile revealed to the world on Thursday is a first, and a step above comparable up-and-coming American designs, missile experts say. “The unique feature of the Oreshnik missile system is that this is a hypersonic medium-range missile flying at a speed of Mach 10,” retired Russian Army colonel and military analyst told Sputnik. “The West does not have missiles that fly at such speeds, or hypersonic missiles in general,” Litovkin said, emphasizing that the Mach 5-5.5 speeds boasted by US missile systems that are in development including Dark Eagle and OpFires program aren’t truly hypersonic – which “begins at Mach 6 or 7,” in the observer’s estimation. 17:00 GMT Russia now has proven hypersonic capability with the Oreshnik, the Mach 10-capable MiG-31-launched Kinzhal missile system, and the Mach 27-ready Avangard hypersonic glider, fitted aboard Russian ICBMs including the UR-100N, Litovkin pointed out. Mach 10 flight speeds mean “the Oreshnik can cause significant damage not only using nuclear or conventional munitions, but also simply with its kinetic force. That is, the impact of the Oreshnik warhead is powerful enough to penetrate concrete, penetrate earth embankments and explode in a deep underground command post, an underground factory, etc. No Western missile has such properties – neither medium-range nor strategic missiles,” Litovkin emphasized. For his part, Russian military observer told Sputnik that while the Dark Eagle and OpFires are still “only undergoing trial operation, testing and development, the Oreshnik has been created, and created on the basis of tried and tested technologies and programs,” which greatly simplifies mass production. Thursday’s real-world combat deployment of the Oreshnik against a military target speaks to the fact that the system is ready for deployment, Kornev said, preempting President Putin's at a defense briefing late on Friday that Russia has already amassed a stockpile of Oreshnik missiles and will continue to test them, "including in combat conditions, depending on the situation and the nature of the security threats that are created for Russia." 14:14 GMT “An element of intrigue here is that we don’t know how many missiles were used – whether it was one missile with these combat capabilities, meaning at least six warheads, or several missiles, which means serial production is probably already underway,” the veteran defense observer explained. Kornev chalks down Russia's ability to rapidly develop and ability to deploy new missile systems to the country's deep-rooted missile design philosophy, which differs greatly from that of the US, in the military expert's estimation. Kornev recalled that during the 1980s between the USSR and the USA, the Soviets' RSD-10 Pioneer missile was designed to ensure strategic deterrence on a continental scale, while the US Pershing and cruise deployments' key goal was to provide Washington with the capability to deliver a strike against enemy targets as quickly as possible from a forward foothold (a strategy which to lives on today with the Pentagon’s highly destabilizing ). “Our system likely has a far greater strike potential in the sense that it was created on the basis of already proven ballistic missile technologies...which means that mass production and rapid deployment of large quantities of the missiles is assured,” Kornev said. "In the case of the West, any similar system will be rather expensive to create." Yesterday, 19:04 GMTUp, up, up! Reeves sends inflation, tax, mortgages, debt and spending through the roof
Oppenheimer & Co. Inc. Makes New $211,000 Investment in Assured Guaranty Ltd. (NYSE:AGO)Olympic wrestler Bajrang Punia suspended for four years by NADA for refusing doping test
A Georgia man has been sentenced in connection to the deaths of a couple that traveled hundreds of miles to buy a car and were found dead in 2015. Ronnie Jay Towns pleaded guilty in connection to the deaths of Elrey "Bud" Runion and June Runion, a couple reported missing in 2015. The couple's remains were found in late January of that same year. The Telfair County Sheriff’s Office announced Towns' plea on social media Monday, Nov. 18. “He has been sentenced to life in prison without the possibility of parole,” the sheriff’s office wrote. “We are thankful to have closure in this case, and our prayers are with both families.” Doctor sentenced: New York City area urologist sentenced to life in prison for sexually abused patients Couple traveled hours to buy vintage car and were never heard from again Elrey Runion, 69, and his wife, 66-year-old June, first went missing in 2015. The Runions were last seen driving their 2003 GMC Envoy. They'd traveled a few hours from Marietta to Telfair County to buy a 1966 Mustang convertible from someone they'd spoken to on Craigslist, according to Reuters. That person turned out to be Towns, who was 28 at the time. The couple's last phone call was to a disposable cell phone Towns owned. That led authorities to interview Towns in connection to their disappearance, Chris Steverson, who was sheriff in 2015, told Reuters at the time. "I don’t think he had a car that was even similar to the one being sought by Mr. Runion," Steverson told Reuters. The outlet reported that it was Towns' own family who helped set up his arrest. Their bodies were found in late January 2015 , and both had been shot in the head, reported the Macon-Telegraph, formerly part of the USA TODAY network. Their bodies had been left among trees off a county road, not far from the pond where their SUV was found. Towns was eventually charged in connection to their deaths. He also faced an armed robbery charge and was accused of giving false statements, the Associated Press reported. Towns initially pleaded not guilty. His first indictment was thrown out because of the way the grand jury was selected, the AP reported. He was indicted again in 2020 but the proceedings were pushed back due to the COVID-19 pandemic. The court proceedings may have also been delayed due to prosecutors seeking the death penalty, which requires extra steps. Towns’ defense attorney, Franklin Hogue, previously told USA TODAY they filed a motion to delay the trial as prosecutors sought the death penalty. New evidence after nearly a decade New evidence was announced in relation to the case in April this year, according to the Georgia Bureau of Investigation, or GBI. Someone found a .22 caliber rifle while magnet fishing in Horse Creek, along Old Prison Camp Road in Telfair County. As the person continued fishing on April 16, they found a bag with the Runions’ drivers’ licenses and credit cards, as well as a cell phone. GBI agents and the Telfair County Sheriff’s Office secured multiple search warrants for a home located in the area and found evidence that was submitted to the crime lab for further analysis. Once new evidence was found, his trial was set for August 2024, the GBI reported. Contributing: Joe Kovac Jr., The Macon-Telegraph S aleen Martin is a reporter on USA TODAY's NOW team. She is from Norfolk, Virginia – the 757. Follow her on Twitter at @SaleenMartin or email her at sdmartin@usatoday.com .Nathan Ake calls on Man City to show character after latest setback
Click App: Trusted Camera (PRNewsfoto/Nodle) Click celebrates significant growth milestones while introducing a new initiative to support and empower photojournalists in sharing authentic, impactful stories through the platform. SAN FRANCISCO , Dec. 11, 2024 /PRNewswire/ -- Click , a groundbreaking mobile app that fights misinformation by making it simple to capture and publish authenticated content, powered by the Nodle Network , has recently launched the Click Photojournalism Fellowship, to empower photojournalists to join Click's mission to build a more truthful future. Joining the fellowship will give photojournalists exposure of their work via the Click app and Nodle Network and allow each photojournalist to share their stories and their photos. Additionally, Click has just reached two growth milestones in its first year of operation, passing 50,000 users and over 1,000 new photos authenticated by Click daily. These follow Click's public beta launch in March. The Click camera app is currently available for download on both iOS or Android , and all content captured with Click can be accessed through the app and on Click's website at clickapp.com . The first two photojournalists to join the Click Fellowship are: "We're thrilled to collaborate with photojournalists, empowering them to share their authentic stories through Click. In an era where digital content authenticity is crucial, we're leveraging blockchain to support journalists in building transparency and trust. The Click Photojournalism Fellowship sets a new standard for credibility in journalistic content on social media," says Micha Benoliel , CEO and co-founder of Intergalactic Labs, the team behind Click and Nodle. Click aims to grow the fellowship to over 20 photojournalists in early 2025 and is currently seeking more photojournalist partners. Photojournalists who join the program will share their recent work via Click's blog (both Click and non-Click photos), that represent their photojournalistic perspective, share their journalist story and be promoted across the Click and Nodle communities. Journalists will also provide feedback on the Click app periodically via scheduled sessions with Click's team. To apply and join the fellowship, photojournalists can fill out this short application and share samples of their work. About Click: Click is a new mobile app empowering everyone to easily create authentic media content. Click is on a mission to combat misinformation and bring truthful photos and videos aka "Deep Reals" to everyone via immutable digital proofs of authenticity. With Click, you can confirm content is real and happened at a specific location, time and via a specific mobile device and camera. This is all made possible by ContentSign , Click's proprietary technology which proves the integrity of data from its moment of capture on-chain. Click is built on ZKsync , the leading Ethereum Layer 2 blockchain and is powered by the Nodle DePIN. Click supports the Coalition for Content Provenance and Authenticity (C2PA) and is a member of the Adobe-led Content Authenticity Initiative (CAI). Download Click on iOS or Android and visit us at clickapp.com to learn more and see recent press coverage. View original content to download multimedia: https://www.prnewswire.com/news-releases/click-camera-app-announces-new-photojournalism-fellowship-as-app-reaches-50-000-users-signing-1-000-authenticated-photos-daily-302329583.html SOURCE NodleLooking Into East West Bancorp's Recent Short Interest
Gaetz withdraws as Trump's pick for attorney general, averting confirmation battle in the Senate WASHINGTON (AP) — Matt Gaetz has withdrawn as Donald Trump’s pick for attorney general following scrutiny over a federal sex trafficking investigation. The Florida Republican made the announcement Thursday. Gaetz’s withdrawal is a blow to Trump’s push to install steadfast loyalists in his incoming administration and the first sign that Trump could face resistance from members of his own party. Trump said in a social media post that Gaetz “did not want to be a distraction for the Administration.” Gaetz said “it is clear that my confirmation was unfairly becoming a distraction to the critical work" of the transition team. He added, “There is no time to waste on a needlessly protracted Washington scuffle.”
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NEW YORK (AP) — Angelina Jolie never expected to hit all the notes. But finding the breath of Maria Callas was enough to bring things out of Jolie that she didn’t even know were in her. “All of us, we really don’t realize where things land in our body over a lifetime of different experiences and where we hold it to protect ourselves,” Jolie said in a recent interview. “We hold it in our stomachs. We hold it in our chest. We breathe from a different place when we’re nervous or we’re sad. “The first few weeks were the hardest because my body had to open and I had to breathe again,” she adds. “And that was a discovery of how much I wasn’t.” In Pablo Larraín’s “Maria,” which Netflix released in theaters Wednesday before it begins streaming on Dec. 11, Jolie gives, if not the performance of her career, then certainly of her last decade. Beginning with 2010’s “In the Land of Blood and Honey,” Jolie has spent recent years directing films while prioritizing raising her six children. “So my choices for quite a few years were whatever was smart financially and short. I worked very little the last eight years,” says Jolie. “And I was kind of drained. I couldn’t for a while.” But her youngest kids are now 16. And for the first time in years, Jolie is back in the spotlight, in full movie-star mode. Her commanding performance in “Maria” seems assured of bringing Jolie her third Oscar nomination. (She won supporting actress in 2000 for “Girl, Interrupted.”) For an actress whose filmography might lack a signature movie, “Maria” may be Jolie's defining role. Jolie's oldest children, Maddox and Pax, worked on the set of the film. There, they saw a version of their mother they hadn't seen before. “They had certainly seen me sad in my life. But I don’t cry in front of my children like that,” Jolie says of the emotion Callas dredged up in her. “That was a moment in realizing they were going to be with me, side by side, in this process of really understanding the depth of some of the pain I carry.” Jolie, who met a reporter earlier this fall at the Carlyle Hotel, didn't speak in any detail of that pain. But it was hard not to sense some it had to do with her lengthy and ongoing divorce from Brad Pitt, with whom she had six children. Just prior to meeting, a judge allowed Pitt’s remaining claim against Jolie, over the French winery Château Miraval, to proceed. On Monday, a judge ruled that Pitt must disclose documents Jolie’s legal team have sought that they allege include “communications concerning abuse.” Pitt has denied ever being abusive. The result of the U.S. presidential election was also just days old, though Jolie — special envoy for the United Nations Refugee Agency from 2012 to 2022 – wasn’t inclined to talk politics. Asked about Donald Trump’s win , she responded, “Global storytelling is essential,” before adding: “That’s what I’m focusing on. Listening. Listening to the voices of people in my country and around the world.” Balancing such things — reports concerning her private life, questions that accompany someone of her fame — is a big reason why Jolie is so suited to the part of Callas. The film takes place during the American-born soprano’s final days. (She died of a heart attack at 53 in 1977.) Spending much of her time in her grand Paris apartment, Callas hasn’t sung publicly in years; she’s lost her voice. Imprisoned by the myth she’s created, Callas is redefining herself and her voice. An instructor tells her he wants to hear “Callas, not Maria." The movie, of course, is more concerned with Maria. It’s Larrain’s third portrait of 20th century female icon, following “Jackie” (with Natalie Portman as Jacqueline Kennedy) and “Spencer” (with Kristen Stewart as Princess Diana). As Callas, Jolie is wonderfully regal — a self-possessed diva who deliciously, in lines penned by screenwriter Steven Knight, spouts lines like: “I took liberties all my life and the world took liberties with me.” Asked if she identified with that line, Jolie answered, “Yeah, yeah.” Then she took a long pause. “I’m sure people will read a lot into this and there’s probably a lot I could say but don’t want to feed into,” Jolie eventually continues. “I know she was a public person because she loved her work. And I’m a public person because I love my work, not because I like being public. I think some people are more comfortable with a public life, and I’ve never been fully comfortable with it.” When Larraín first approached Jolie about the role, he screened “Spencer” for her. That film, like “Jackie” and “Maria,” eschews a biopic approach to instead intimately focus on a specific moment of crisis. Larraín was convinced Jolie was meant for the role. “I felt she could have that magnetism,” Larraín says. “The enigmatic diva that’s come to a point in her life where she has to take control of her life again. But the weight of her experience, of her music, of her singing, everything, is on her back. And she carries that. It’s someone who’s already loaded with a life that’s been intense.” “There’s a loneliness that we both share,” Jolie says. “That’s not necessarily a bad thing. I think people can be alone and lonely sometimes, and that can be part of who they are.” Larraín, the Chilean filmmaker, grew up in Santiago going to the opera, and he has long yearned to bring its full power and majesty to a movie. In Callas, he heard something that transfixed him. “I hear something near perfection, but at the same time, it’s something that’s about to be destroyed,” Larraín says. “So it’s as fragile and as strong as possible. It lives in both extremes. That’s why it’s so moving. I hear a voice that’s about to be broken, but it doesn’t.” In Callas’ less perfect moments singing in the film, Larraín fuses archival recordings of Callas with Jolie’s own voice. Some mix of the two runs throughout “Maria.” “Early in the process,” Jolie says, “I discovered that you can’t fake-sing opera.” Jolie has said she never sang before, not even karaoke. But the experience has left her with a newfound appreciation of opera and its healing properties. “I wonder if it’s something you lean into as you get older,” Jolie says. “Maybe your depth of pain is bigger, your depth of loss is bigger, and that sound in opera meets that, the enormity of it.” If Larraín’s approach to “Maria” is predicated on an unknowingness, he's inclined to say something similar about his star. “Because of media and social media, some people might think that they know a lot about Angelina,” he says. “Maria, I read nine biographies of her. I saw everything. I read every interview. I made this movie. But I don’t think I would be capable of telling you who she was us. So if there’s an element in common, it’s that. They carry an enormous amount of mystery. Even if you think that you know them, you don’t.” Whether “Maria” means more acting in the future for Jolie, she's not sure. “There's not a clear map,” she says. Besides, Jolie isn't quite ready to shake Callas. “When you play a real person, you feel at some point that they become your friend,” says Jolie. “Right now, it’s still a little personal. It’s funny, I’ll be at a premiere or I’ll walk into a room and someone will start blaring her music for fun, but I have this crazy internal sense memory of dropping to my knees and crying.” Jake Coyle, The Associated Press
AP News Summary at 4:42 p.m. ESTU.S. President Joe Biden boards Air Force One prior to departure from Galeao International Airport in Rio De Janeiro, Brazil, on Nov. 19, as he returns to Washington following the G20 Summit. SAUL LOEB/AFP/Getty Images John Rapley is an author and academic who divides his time among London, Johannesburg and Ottawa. His books include Why Empires Fall (Yale University Press, 2023) and Twilight of the Money Gods (Simon and Schuster, 2017). The tragedy of Joe Biden is that after setting out to be the most transformative American president since Ronald Reagan, he will ultimately be of little consequence, remembered mainly for foreign-policy failures such as the crisis in Gaza or the Taliban’s return to Afghanistan. Domestically, his successful revival of industrial policy, which appeared to have launched a genuine renewal of the country’s productive capacity, will be quickly shelved by Donald Trump. And given how easily Bidenomics will go the way of Betamax and the BlackBerry, it seems unlikely a future president will ever want to try something similar again. But it would be premature to conclude that the United States’ brief but ill-fated experiment with industrial policy signals its demise. It continues to be used elsewhere, most notably in China. This will be to the United States’ detriment. Mr. Trump’s belief is that in a competition with China, the U.S.’s best hope lies in a small-state, free-market approach. Take his approach to Mr. Biden’s Inflation Reduction Act, which subsidized renewable energy and electric-vehicle producers to speed up the country’s energy transition. The president-elect wants to roll it back. Mr. Trump, who is on record inexplicably saying climate change is a Chinese hoax, also maintains that Mr. Biden’s promotion of EV sales would lead to the “complete obliteration” of the American automobile industry. The incoming president is instead saying that his “energy dominance” strategy will make American industry great again. He aims to cut taxes, roll back government and ease environmental restrictions on oil companies, in the stated hope that a flood of cheap energy will reinvigorate American car companies, stir new investment, open the door to a revival of manufacturing and stimulate the growth of artificial intelligence (whose energy demands are ravenous). This is not a bet without considerable risks. A growing body of analysts maintains that the end of the internal-combustion engine is upon us. They say EVs are a superior technology that’s destined to render cars with internal-combustion engines obsolete, the way those cars once made horse-drawn carriages obsolete. A recent report by Goldman Sachs went so far as to say that the tipping point – the point at which it becomes more expensive to run a vehicle with an internal-combustion engine – could come in as little as two years. Thereafter, as happened when home computers came on the scene and some people clung to their typewriters as desktops and then laptops took over the world, some will still nostalgically cling to their gas-guzzlers whilst rapidly becoming a dying breed. Thanks to its own industrial policy, China has raced ahead of Western countries in renewable technology. This happened so fast it took Western countries by complete surprise – in large measure because CEOs , shut out of China by COVID lockdowns for a couple of years, returned to find the Chinese had completely overtaken them. Some analysts now believe Western countries are so far behind that there’s no hope of ever catching up. Mr. Biden was hoping that subsidies and targeted protection would accelerate the development of the U.S.’s EV and renewables sector. Admittedly, the results were mixed, since industrial policy is hard and the U.S. bureaucracy may not have been up to the task of implementing it. But things were starting to move forward. The looming reversal of Bidenomics just as it was starting to bear fruit may, in fact, produce a short-term boom that appears to vindicate Mr. Trump. But it could also leave Tesla, whose chief executive Elon Musk is a prominent backer of Mr. Trump, as the lone domestic EV champion. That would largely abandon the growing market for EVs to China , which means that if a tipping point does come and Tesla isn’t able to out-compete Chinese producers, the U.S. may ultimately end up going backward. Meanwhile, a manufacturing revival looks to be at most a short-term cure. While Mr. Trump’s proposed tariffs will in fact lead to some import-substitution, many of the firms that benefit will not be globally competitive, resulting in higher prices for American consumers. As for AI, behind the hype, there are growing s igns that a killer app that transforms the economy, the way the energy transition is currently doing in China, may never emerge. If the AI boom goes the way of the turn-of-the-millennium dot-com boom – lots of excitement, soaring stock markets and an eventual crash – just as China’s manufacturers take ever more global market share, it will vindicate Mr. Biden, albeit too late. In that case the epitaph will say industrial policy is dead, long live industrial policy. Unfortunately for the U.S., it will be China’s industrial policy.Menarini Group and MEDSIR Present the Phase III Study ADELA: A New Therapeutic Strategy for Advanced Breast Cancer
Browns’ Jerry Jeudy has a great chance to make the Broncos look silly for trading him in Denver on Monday nightSACRAMENTO, Calif. , Dec. 11, 2024 /PRNewswire/ -- Azimuth AI Inc. a startup specializing in producing highly customized silicon products for edge and embedded computing markets has closed a $11.5M venture round. Founded in 2022, Azimuth AI is focused on developing purpose-built SoCs (System-on-chip) products for, smart city, 2/3-wheeler vehicles, and other edge computing applications. The Team at Azimuth has designed and delivered 30+ silicon products to market working at leading semiconductor companies in the Silicon Valley and India . Currently Azimuth AI has offices in Sacramento , USA and Hyderabad, India . The venture round was led by Cyient , a global Intelligent Engineering services company headquartered in Hyderabad, India . The company had announced previously that the strategic investment to acquire a stake in Azimuth AI, marks a significant milestone in its efforts to expand its capabilities and drive innovation across the semiconductor industry. Cyient Executive Vice-Chairman & Managing Director Krishna Bodanapu said the acquisition will enhance the company's capabilities in the critical semiconductors space while reinforcing its commitment to next-gen power and energy solutions. Ramya Mohan , Chief Strategy Officer at Cyient commented that the global semiconductor industry is a $600 billion industry, and it is expected to grow to more than $1 trillion by 2030. While the general-purpose chip market exists, the Application-Specific Integrated Circuit (ASIC) market is growing three times faster. This growth is driven by companies seeking differentiation at the chip level which is the focus at Azimuth AI. Moneta Ventures , a Sacramento based venture capital firm co-led the round that was also joined by another local Sacramento firm Growth Factory . Ashu Bhalla , Partner at Moneta Ventures, remarked, "We are passionate about investing in innovative companies that tackle complex challenges with transformative solutions. Azimuth's expertise in developing SoCs tailored to specific market segments, coupled with their ability to deliver significant cost advantages to customers, is truly outstanding. Their exceptional strengths in product innovation, technology, and customer acquisition were key drivers behind our decision to back their team." Azimuth's seed round investor AUM ventures , a venture capital firm based in the Abu Dhabi Global Market (ADGM) also re-invested in this round. Chetan Mehta , Founding Partner at AUM Ventures expressed that, "We are thrilled to double down on our investment in Azimuth. Over the past year, the team has come together with decades of expertise in building silicon products. With the semiconductor industry poised for rapid growth over the next decade, custom silicon chips are redefining innovation by delivering specialized solutions to meet the evolving needs of diverse markets and applications." Sri Badiga and Praveen Yasarapu , Co-founders at Azimuth AI said, "We are thrilled to welcome Krishna Bodanapu , Ramya Mohan , and Ashu Bhalla to join our Board of Directors. Guidance and partnership from such renowned industry leaders will provide invaluable perspectives to our strategic decision-making. From shaping the future of emerging technologies to navigating complex global markets, these senior leaders have consistently demonstrated the vision and execution needed to achieve extraordinary outcomes." The startup will use the fresh capital for productizing its first-generation SoC for a leading global Original Equipment Manufacturer (OEM). The funds will also be used to grow the team and partnerships to develop a roadmap of cutting-edge SoCs that not only champion environmental sustainability but also facilitate affordable access to computing solutions in cost-challenged markets. Azimuth AI was represented by Castle Placement LLC as its investment banker for this round. View original content to download multimedia: https://www.prnewswire.com/news-releases/azimuth-ai-edge-computing-silicon-company-closes-11-5-million-in-funding-302329582.html SOURCE Azimuth AI Inc.
The Moscow-friendly Georgian Dream party, fresh off a contested victory in parliamentary elections last month that ignited calls for fresh polls and pro-EU demonstrations in Tbilisi, is preparing to hold its first parliamentary session on November 25. In comments to RFE/RL, Parliament Speaker Shalva Papuashvili said that foreign diplomats would not be invited to attend the opening session, saying it “should only be celebrated by the Georgian people." EU and other Western officials have expressed serious doubts about the October 26 elections in which Georgian Dream officially won 53.9 percent of the vote. Opposition leaders this week called on foreign diplomats not to legitimize the new parliament by attending the first session of parliament. Georgian President Salome Zurabishvili has refused to recognize the result validated by the country’s Central Election Committee (CEC), and protests demanding new elections continue to be held in the country’s capital. Protesters have alleged that there was widespread fraud during the campaign and vote, and that Russia heavily influenced the outcome favoring Georgian Dream, which has been in power since 2012. In recent days, Georgian police have shut down the demonstrations, including through the use of violence on November 19. Video footage by RFE/RL correspondents in Tbilisi showed police dragging people to the ground, including women, and beating them before taking them away. The same day, Zurabishvili filed a lawsuit in the Constitutional Court "requesting annulment of the election results as unconstitutional.” The first item on the agenda for the opening session, which will be attended by the head of the CEC, will be recognizing the authority of all 150 parliament members. Georgia has been a candidate for EU membership since last year, but a "foreign influence" law and anti-LGBT measures enacted under Georgian Dream’s leadership have stalled that effort. The United States in July announced that it would pause more than $95 million in assistance to the Georgian government, warning it that it was backsliding on democracy. U.S. President-elect Donald Trump is considering tapping Richard Grenell, his former intelligence chief, to be a special envoy for the Russia-Ukraine conflict, according to four sources familiar with the transition plans. Grenell, who served as Trump's ambassador to Germany, as special envoy to Serbia-Kosovo talks, and was acting director of national intelligence during Trump's 2017-2021 term, would play a key role in Trump's efforts to halt the war if he is ultimately selected for the post. While there is currently no special envoy dedicated solely to resolving the Russia-Ukraine conflict, Trump is considering creating the role, according to the four sources. Grenell has advocated for the creation of "autonomous zones" as a means of settling the conflict. He also suggested he would not be in favor of Ukraine joining the North Atlantic Treaty Organization in the immediate future. EU Parliament President Roberta Metsola supports the use of long-range missiles by Ukraine in its defense against Russia's full-scale invasion and said Germany should quickly deliver its long-range Taurus system to the embattled country. Metsola, in an interview published on November 23 by the Funke Mediengruppe newspapers, said "yes," when asked whether countries providing long-range missiles to Ukraine should allow it to use them against targets in Russia -- and whether Germany should deliver its Taurus weapons system to Ukraine. Chancellor Olaf Scholz, a Social Democrat, has been staunchly opposed to sending Taurus missiles to Ukraine. His coalition partners, the pro-business Free Democrats and the Greens, however, are in favor of sending Kyiv the missiles. Austria has dropped its long-standing veto to Bulgaria and Romania joining the passport free Schengen zone, opening the door to their accession next year. The breakthrough development was announced on November 22 by the Hungarian presidency of the EU Council, which hosted a meeting in Budapest with the interior ministers of Romania, Bulgaria, and Austria. The EU will meet with the two candidate countries to finalize a joint security package at a meeting on December 11-12. The two countries could become Schengen members in January. “Bulgaria and Romania belong fully to the Schengen area. I welcome the positive outcome of informal discussions in Budapest today.” Ursula von der Leyen, the president of the European Commission, said in a tweet following the announcement. The addition of Bulgaria and Romania will expand the Schengen zone to 28 states, including 24 EU members. Ireland and Cyprus will remain the only EU members not part of the Schengen Area. Bulgarians and Romanians currently are not permitted to travel freely into other Schengen member states over land borders. Early this year, they received the right to travel freely by air and sea in the first concession by Vienna. After the meeting in Budapest, Hungarian Interior Minister Sandor Pinter told media that the agreement to be signed next month includes the establishment of a special contingent of at least 100 border police officers on the Turkish-Bulgarian border. Hungary will contribute to the full deployment of the officers and provide the necessary technical equipment to ensure effective protection of the border, he said. Pinter expressed confidence that the issue could be resolved by December 31. EU Commissioner for Home Affairs Ylva Johansson said a January accession date is a realistic goal. Yekaterina Neroznikova, a journalist and member of the Marem human rights group, is facing administrative charges in Russia for her alleged involvement with an "undesirable organization." The charges stem from Neroznikova's participation in an interview with RFE/RL earlier this year, where she discussed the high-profile abduction of Seda Suleimanova, a native of Chechnya. The administrative protocol was filed with the Zhukovsky City Court in Moscow Oblast on November 15, with a hearing scheduled for November 26. Neroznikova, who left Russia following the full-scale invasion of Ukraine, disclosed the development to the OVD-Info human rights group, a prominent watchdog monitoring political persecution in Russia. The case against Neroznikova is linked to her April 2024 appearance on RFE/RL’s program Human Rights Are A Right. During the program, she discussed the abduction of Suleimanova, who was forcibly taken from St. Petersburg in August 2023 by local police and Chechen operatives. Suleimanova, who fled Chechnya in 2022 because of pressure being put on her to agree to a forced marriage, has been missing since September last year. The charges against Neroznikova are seen as part of Russia’s broader crackdown on dissent and press freedom. Suleimanova's case has prompted global protests and solidarity campaigns highlighting ongoing human rights concerns in Chechnya and Russia in general. According to Neroznikova, a man identifying himself as an officer of the Interior Ministry contacted her relatives last week before reaching out to her directly. He informed her of the administrative charges, citing her commentary on RFE/RL as the reason. RFE/RL's Russian Service and its multiple projects in the Russian language were designated as "undesirable organizations" in Russia in February 2024, making any association with them punishable under Russian law. Participation in the activities of an “undesirable organization” in Russia can result in fines of up to 15,000 rubles for individuals. Repeat offenses within a year can escalate to criminal charges, carrying penalties of up to four years in prison. Suleimanova's case has drawn international attention. In 2022, she fled her family in Chechnya to avoid an arranged marriage and persistent conflicts. In August 2023, she was abducted in St. Petersburg by individuals including local police and plainclothes Chechen security officers. She was taken to her family in Chechnya, and no information about her whereabouts has been available since September 2023. An investigation into Suleimanova’s disappearance was launched in March 2024 following thousands of public appeals. Despite the family's claims that she left home again in February, observers remain skeptical, citing conflicting statements made by her relatives. Russian President Vladimir Putin said the country's new intermediate-range ballistic missile, a nuclear-capable weapon, will continue to be tested, including in combat conditions, as Moscow struck several Ukrainian regions with other, less powerful weapons. "We will continue these tests, including in combat conditions, depending on the situation and the nature of the security threats that are created for Russia," Putin said on November 22 at a meeting with Defense Ministry officials and military-industrial complex officials. The Kremlin leader also called for serial production of the large missile to begin. Russia launched the so-called Oreshnik ballistic missile against Ukraine on November 21 in a strike targeting the city of Dnipro. Putin said at the time it was part of Moscow's response to Ukrainian attacks on Russian soil with U.S.-supplied ATACMS and British-supplied Storm Shadow missiles. The use of the Oreshnik "is first and foremost a messaging and saber rattling kind of weapon. This is the sort of delivery system that's not cheap. It's not a battlefield sort of weapon," Tom Karako, a missile defense expert at the Center for Strategic and International Studies in Washington, told RFE/RL. Putin added on November 22 that the Oreshnik is new and not an upgrade of previous Soviet-designed weaponry. The United States said the new missile is “experimental” and based on Russia’s RS-26 Rubezh intercontinental ballistic missile (ICBM). Ukraine initially accused Russia of having used an ICBM in the Dnipro attack. An ICBM has never been used in a war. Strategic Weapons Russia has been striking Ukraine with Iskanders, ground-launched, short-range ballistic missiles, and Kinzhals, air-launched, intermediate-range ballistic missiles, as well as various cruise missiles. Russia probably only has several units of the Oreshnik in stock, a U.S. official told media following the November 21 strike. Ukraine's military intelligence put the figure at up to 10 units. If Russia were to move forward with serial production of the Oreshnik, it would be for its nuclear force posture and not for use in a conventional war like the one with Ukraine, Karako said. "This is not an alternative to a cruise missile. It's probably designed for strategic weapons," he said. Zelenskiy's Response In his November 21 address to the nation announcing the use of the Oreshnik, Putin said that the missile traveled at a speed of Mach 10, or 2.5-3 kilometers per second, claiming that "there are currently no ways of counteracting this weapon." Meanwhile, Ukrainian President Volodymyr Zelenskiy said on November 22 that Ukraine was working on developing new types of air defenses to counter "new risks," a reference to missiles like the Oreshnik. In his nightly video address, Zelenskiy said testing a new weapon for the purposes of terror in another country was an "international crime" and called for a worldwide "serious response" to keep Russia from expanding the war. "When someone starts using other countries not only for terror, but also for testing their new missiles through acts of terror, then this is clearly an international crime." A lack of air defenses has been one of Ukraine's major weak spots in the 33-month war with Ukraine. Zelenskiy has called on the West to deliver more air defense systems since the first days of the invasion. He had also called on the West to ease restrictions preventing Ukraine from striking inside Russia with powerful long-range weapons. Zelenskiy said the deep strikes were necessary to target airfields critical for Russia's daily aerial attacks. The United States and the United Kingdom reportedly lifted the restrictions on November 17 with Ukraine using their long-range weapons -- ATACMS and Storm Shadow respectively -- to hit targets in Russia's regions of Belgorod and Kursk. Putin launched the Oreshnik into Ukraine to warn the West against arming Ukraine. Parliament Session Canceled Russia did not use the Oreshnik to strike Ukraine during another deadly air attack on November 22. Two people were killed and 12 wounded in Russian strikes on Sumy, Artem Kobzar, the mayor of the northeastern Ukrainian city, reported in a video statement on Telegram. The Ukrainian Air Force said Russian drone attacks were under way in four regions -- Sumy, Kyiv, Chernihiv, and Zhytomyr. In the capital, which has been on edge for several days amid intense Russian attacks on Ukraine, lawmakers were advised to avoid the government district on November 22 and parliament canceled a scheduled session due to warnings of a potential missile strike. "We were informed about the risk of a missile strike on the Verkhovna Rada in Kyiv in the coming days. Putin has significantly raised the stakes . Tomorrow's parliamentary session is canceled," lawmaker Taras Batenko said. Oleksiy Honcharenko, another lawmaker, said on Telegram that the next session was now planned for December, although parliament leaders have not officially commented on the warnings. Zelenskiy's office assured the public that the presidential administration would continue operating "as usual" on November 22. The Russian Supreme Court has declared the international organization Post-Russia Free Nations Forum a terrorist group, the latest move in the Kremlin's clampdown on any sign of dissent. The organization, founded in Poland in 2022, has been accused of promoting separatism and aiming to disband the Russian Federation into independent states under foreign influence. Russia is a multiethnic state comprised of more than 80 regions, many of which have large indigenous populations, such as Chechnya and Tatarstan. Since coming to power in 1999, Russian President Vladimir Putin has centralized authority, curtailing the autonomy that some ethnic regions enjoyed. Russia's invasion of Ukraine and its attempt to wipe out Ukrainian identity has shone a bright light on the Kremlin's historical mistreatment of its own indigenous populations and triggered a "decolonization" movement that seeks to give more prominence to ethnic groups within Russian historical and cultural studies. The case against the Post-Russia Free Nations Forum was launched in late October by the Prosecutor-General’s Office, which cited its activities as a threat to Russia’s territorial integrity and national security. In its statement, the Prosecutor General’s Office alleged that the forum operates through 172 regional and national entities, including the Baltic Republican Party, the Ingria Movement, the Congress of Peoples of the North Caucasus, the Free Yakutia Foundation, and the Far Eastern Confederation. The office claims these groups are directed by exiled leaders of separatist movements. “These leaders aim to divide the Russian Federation into independent states that would fall under the influence of hostile foreign countries,” the Prosecutor-General’s Office stated on its official website. The Post-Russia Free Nations Forum is registered in Poland and describes itself as a civic movement advocating for greater regional autonomy within Russia, with some members supporting full independence for regions. On its website and social media platforms, the organization also uses variations of its name, such as the Post-Russia Free States Forum. Ukrainian businessman Oleh Mahaletskiy positions himself as one of the founders of the group and is believed to be a major sponsor. The group’s activities have included discussions on decentralization and independence, with notable speakers such as the noted Tatar activist Nafis Kashapov, Bashkir activist Ruslan Gabbasov, Russian opposition politician Ilya Ponomaryov, U.S. political analyst Janusz Bugajski, and others. Following the November 22 terrorist designation by the Supreme Court, all activities of the Post-Russia Free Nations Forum are now banned in Russia. Membership or association with the group is subject to criminal prosecution under Russian anti-terrorism laws. Critics of the ruling argue that the designation reflects a broader crackdown on dissent and regional autonomy movements in Russia. They note that the Forum primarily operates abroad and online, raising questions about the ruling’s effectiveness outside Russian borders. The Forum has not yet responded to the court’s decision. Observers suggest that this ruling may escalate tensions between Russia and countries hosting members of the organization, particularly Poland, where it is registered. The authoritarian ruler of Belarus, Alyaksandr Lukashenka, has threatened to shut down the Internet in the event of mass protests during or after the upcoming presidential election, after the previous vote in 2020 erupted in unprecedented unrest amid opposition allegations it was rigged. Speaking to students at Minsk State Linguistic University on November 22, Lukashenka defended past Internet restrictions and warned of future measures to throttle dissent. "If this happens again, we will shut it down entirely. Do you think I will sit idly and pray you don't send a message when the fate of the country is at stake?" state news agency BelTA quoted him as saying. Lukashenka admitted that Internet disruptions during the 2020 protests were conducted with his approval, citing the need to "protect the country." Following the August 9, 2020, election, which many Western governments have said was not free and fair, Internet access across Belarus was disrupted for several days and intermittently blocked. The disputed election that extended Lukashenka's decades of rule -- he has held power since 1994 -- for another term was widely condemned as fraudulent by the United States, the European Union, and other international actors. The protests, which demanded Lukashenka’s resignation, were met with mass arrests, alleged torture, and violent crackdowns that left several people dead. Many opposition leaders remain imprisoned or in exile, while Lukashenka refuses dialogue with his critics. The next presidential election in Belarus is scheduled for January 26. Alsu Kurmasheva, a journalist for RFE/RL's Tatar-Bashkir Service, was honored with the International Press Freedom Award by the Committee to Protect Journalists (CPJ) in a ceremony held in New York on November 21. Kurmasheva, who was recently released from detention in Russia after spending 288 days in custody, thanked the CPJ for its efforts toward gaining her freedom. "Journalism is not a crime," she said , noting that more than 20 journalists are currently imprisoned in Russia. Kurmasheva added that she was dedicating the award to her colleagues still imprisoned , including RFE/RL journalists Ihar Losik and Andrey Kuznechyk in Belarus, Vladislav Yesypenko in Crimea, and Farid Mehralizada in Azerbaijan. "My colleagues are not just statistics; like me they are real human beings with families who miss and love them. There are dozens of other journalists in Russian prisons. They should be released at once," Kurmasheva stressed . Other recipients of the award this year included Palestinian journalist Shorouq al-Aila, Guatemalan journalist Kimi de Leon, and Nigerien investigative journalist Samira Sabou, all recognized for their courage in the face of persecution. Detained by authorities in June 2023 as she was visiting relatives in the central Russian city of Kazan, Kurmasheva was initially charged with not declaring her U.S. passport. She was released but barred from leaving the country. That October, however, she was arrested, jailed, and charged with being an undeclared "foreign agent" -- under a draconian law targeting journalists, civil society activists, and others. She was later hit with an additional charge: distributing what the government claims is false information about the Russian military, a charge stemming from her work editing a book about Russians opposed to the ongoing invasion of Ukraine. RFE/RL, as well as the U.S. government, called the charges absurd. The prisoner exchange that came to fruition on August 1 included 24 people in all -- including Kurmasheva, Wall Street Journal reporter Evan Gerskovich, and Russian political activist Vladimir Kara-Murza -- in a complex, seven-country deal. Religious tensions are on the rise in northwestern Pakistan following a deadly attack on a police-escorted convoy of Shi'ite Muslims that threatened to reignite sectarian violence in a strife-plagued region of Khyber Pakhtunkhwa Province. In the aftermath of the attack on the 200-vehicle convoy traveling from Peshawar to Parachinar, the capital city of the Kurram district, authorities on November 22 imposed a curfew and suspended mobile service in the remote mountainous district. RFE/RL correspondents on the ground reported on November 22 that heavily armed people set fire to a military checkpoint in the area overnight. In Parachinar, dozens of angry people carrying automatic weapons were gathering, amid reports that several other facilities of the Pakistani Army and the paramilitary Frontier Constabulary were attacked and destroyed, with RFE/RL correspondents reporting sounds of constant heavy gunfire. Jamshed Shirazi, a social activist in Parachinar, told RFE/RL that several government installations had been damaged by the angry protesters. "People are expressing their anger by attacking the government offices," Shirazi said. But Jalal Hussain Bangash, a local Shi'ite leader, voiced dismay at the violence during a Friday Prayer sermon on November 22 and said that Shi'a had nothing to do with the ensuing violence, RFE/RL correspondents on the ground report . Hamid Hussain, a lawmaker from Kurram in the national parliament, was adamant that the violence was the work of provocateurs. "We are helpless. Neither Shi'a nor Sunnis are involved in this. This is some other invisible forces who do not want to see peace in the area," Hussain told RFE/RL. At least 48 people, including several women and children, were killed and more than 40 wounded when gunmen opened fire on November 21 on the convoy of vehicles in the Kurram district of Khyber-Pakhtunkhwa province near the Afghan border. Local leaders told RFE/RL that most of those killed were Shi'a, but at least four Sunnis were also among the dead. No one has taken responsibility for the attack, the latest in a series of deadly confrontations in Kurram, long known as a hotspot of Shi'ite-Sunni sectarian conflict. Local tribal leader Malik Dildar Hussain told RFE/RL that there were about 700 people in the convoy. Tensions in Kurram began to heat up in the past several months, where clashes again erupted between Sunni and Shi'ite Muslim tribes in the area, which was formerly semiautonomous. On October 12, 17 people were killed in an attack on a convoy, and there have been a handful of deadly attacks since then. Sunnis and Shi'a live together in Kurram and have clashed violently over land, forests, and other property as well as religion over the years, despite government and law enforcement efforts to build peace. Minority Shi'ite Muslims have long suffered discrimination and violence in Sunni-majority Pakistan. Moscow launched another deadly attack on Ukraine on November 22, a day after firing what it said was a new intermediate-range missile that the Kremlin boasted was a " warning " for the West, after Kyiv reportedly obtained permission from President Joe Biden to strike into Russia with U.S. long-range missiles. Two people were killed and 12 wounded in Russian strikes on Sumy, Artem Kobzar, the mayor of the northeastern Ukrainian city, reported in a video statement on Telegram. Ukraine's air force said Russian drone attacks were under way in four regions -- Sumy, Kyiv, Chernihiv, and Zhytomyr. In the capital, which has been on edge for several days amid intense Russian attacks on Ukraine, lawmakers were advised to avoid the government district on November 22 and parliament canceled a scheduled session due to warnings of a potential missile strike. "We were informed about the risk of a missile strike on the Verkhovna Rada in Kyiv in the coming days. Putin has significantly raised the stakes . Tomorrow's parliamentary session is canceled," lawmaker Taras Batenko said, while lawmaker Oleksiy Honcharenko said on Telegram that the next session was now planned for December, although parliament leaders have not officially commented on the warnings. The office of President Volodymyr Zelenskiy assured the public that it would continue operating "as usual" on November 22. On November 20, the U.S. Embassy in Ukraine warned of a significant Russian air attack, prompting the temporary closure of its operations. The embassies of Spain, Italy, and Greece also suspended services for the day. On November 21, Russian President Vladimir Putin announced the "successful combat testing" of a new Oreshnik (Hazel Tree) intermediate-range ballistic missile amid the Kremlin's full-scale invasion of Ukraine. Putin claimed the missile was used in a strike on Ukraine's eastern city of Dnipro, asserting it was a response to NATO’s "aggressive actions" and Ukraine’s use of Western-supplied missiles to target Russian territory. On November 22, Kremlin spokesman Dmitry Peskov reiterated that the test was a message to the West that Moscow will respond harshly to any "reckless" Western moves in support of Ukraine. "The main message is that the reckless decisions and actions of Western countries that produce missiles, supply them to Ukraine, and subsequently participate in strikes on Russian territory cannot remain without a reaction from the Russian side," Peskov told reporters. "The Russian side has clearly demonstrated its capabilities, and the contours of further retaliatory actions in the event that our concerns are not taken into account have been quite clearly outlined," he said. Ukraine's military intelligence said on November 22 that Russia may have up to 10 units of the new missile. Hungarian Prime Minister Viktor Orban has invited his Israeli counterpart to visit Hungary, defying an arrest warrant for issued by the International Criminal Court (ICC) for Benjamin Netanyahu that other European states say they will honor. Orban, speaking during his regular weekly interview with Hungarian state radio, said on November 22 that the ICC's decision a day earlier to issue the warrant accusing Netanyahu of "crimes against humanity and war crimes" committed during the war in Gaza was "outrageously brazen" and "cynical." The ICC issued similar arrest warrants for former Israeli Defense Minister Yoav Gallant and a Hamas military leader who Israel claims to have killed but whose death the U.S.- and EU-designated terrorist group has not officially acknowledged. The ICC said Netanyahu and Gallant were suspected of using "starvation as a method of warfare" by restricting humanitarian aid while targeting civilians in Israel's war in Gaza -- charges Israeli officials deny. Orban said the ICC move against Netanyahu "intervenes in an ongoing conflict...dressed up as a legal decision, but in fact for political purposes." "Later today, I will invite the Israeli prime minister, Mr. Netanyahu, to visit Hungary, where I will guarantee him, if he comes, that the judgment of the ICC will have no effect in Hungary, and that we will not follow its terms," he added. "There is no choice here, we have to defy this decision," Orban said. Shortly after the ICC decision was announced, the European Union's top diplomat, Josep Borrell, said ICC decisions "are binding on all states party to the Rome Statute, which includes all EU member states." However, the EU's most powerful members, Germany and France, on November 22 reacted with restraint to the ICC warrants. A spokesman said the German government will refrain from any moves until a visit to Germany by Netanyahu is planned. "I find it hard to imagine that we would make arrests on this basis," Steffen Hebestreit said on November 22, adding that legal questions had to be clarified about the warrant. In Paris, Foreign Ministry spokesman Christophe Lemoine only said that France acknowledged the ICC's move and voiced its support for the ICC's independence. "France takes note of this decision. True to its long-standing commitment to supporting international justice, it reiterates its attachment to the independent work of the court, in accordance with the Rome Statute," Lemoine said. Hungary, a NATO and European Union member state, has signed and ratified the 1999 document. However, it has not published the statute's associated convention and therefore argues that it is not bound to comply with ICC decisions. Netanyahu on November 22 thanked Orban for his show of "moral clarity." "Faced with the shameful weakness of those who stood by the outrageous decision against the right of the State of Israel to defend itself, Hungary" is "standing by the side of justice and truth," Netanyahu said in a statement. A right-wing nationalist in power since 2010, Orban has maintained close relations with Russian President Vladimir Putin and has voiced opposition to the EU's sanctions imposed on Moscow after its unprovoked invasion of Ukraine in February 2022. Orban has previously said that Hungary would not arrest Putin either, despite the ICC arrest warrant issued on the Russian leader's name for war crimes for his role in deporting Ukrainian children. Furthermore, he flew to Moscow in July immediately after Hungary took over the EU's rotating six-month presidency to meet with Putin, in defiance of the fellow members of the bloc. Soltan Achilova, a veteran journalist and former RFE/RL correspondent in Turkmenistan, was forcibly hospitalized in Ashgabat on November 20 in what appears to be a move by the government to prevent her from flying to Geneva to receive an international award. According to the Chronicle of Turkmenistan website, four men in medical gowns arrived at the 75-year-old's apartment early that morning, claiming she was suspected of carrying an infectious disease and needed an "urgent" examination. Achilova, who showed no signs of illness, was forcibly taken to the Center for the Prevention and Treatment of Infectious Diseases in Ashgabat's Choganly district. Her family was not allowed to accompany her and her apartment keys were confiscated. One family member said one of the men told Achilova, "Why do you need keys in the afterlife?" Doctors have not disclosed when she will be released. Turkmenistan is consistently ranked by media watchdogs, such as Reporters Without Borders (RSF), among the worst countries in the world for press freedom. Independent media are nonexistent in the authoritarian Central Asian state, where journalism "amounts only to praise for the regime," according to RSF. The government continues a relentless clampdown on dissent -- with critics being harassed, beaten, tortured, jailed, and even killed. Many others have been forced abroad into exile. Human rights groups, including the Turkmen Initiative for Human Rights and the International Partnership for Human Rights, immediately condemned Achilova's forced detention, calling it a stark escalation in Turkmenistan's crackdown on free speech. They demanded her immediate release and an end to the persecution of journalists. Achilova, the only journalist in Turkmenistan who openly criticizes the authoritarian government, has faced repeated harassment, threats, and attacks. In November 2023, border guards at the Ashgabat airport destroyed her passport to prevent her from traveling to Switzerland, where she was scheduled to attend the Martin Ennals Award human rights ceremony. Achilova has faced verbal threats and physical attacks, which the journalist and her supporters describe as government retaliation for her work. Many of her relatives have also been threatened. Ashgabat doesn't tolerate any dissent, and the government has stifled independent media, forced opposition activists into exile, and blocked access to all major social media and messaging apps to virtually cut its citizens off from the rest of the world. The Teatro San Carlo in Naples, Italy, has canceled appearances by opera singer Ildar Abdrazakov over his support for Russian President Vladimir Putin. Pina Picierno, a vice president in the European Parliament, announced the cancellation on the social network X on November 21, emphasizing that Abdrazakov's ties to the Kremlin made him unfit for a leading cultural institution in Europe. She had led a campaign to keep Abdrazakov from performing in productions of Verdi’s Don Carlos and Attila operas. The Anti-Corruption Foundation of Aleksei Navalny had previously named Abdrazakov, who comes from the Bashkortostan region, as a regime supporter, citing his performances at events tied to Russian Defense Minister Sergei Shoigu and a lucrative appearance on Red Square in 2022. This marks the latest in a series of international cancellations for Abdrazakov, whose scheduled performances in the United States and Germany were also recently cancelled. To read the original story by RFE/RL's Idel.Realities, click here . Iran has vowed to respond to a resolution adopted by the United Nations' nuclear watchdog that criticizes the Islamic republic for what it says is poor cooperation by installing a number of "new and advanced" centrifuges. The resolution, which comes shortly after the return of International Atomic Energy Agency (IAEA) chief Rafael Grossi from a trip to Iran , reportedly says it is "essential and urgent" for Tehran to "act to fulfill its legal obligations." A joint statement by Iran's Foreign Ministry and Atomic Energy Organization said on November 22 that the country's nuclear chief, Mohammad Eslami, "issued an order to take effective measures, including launching a significant series of new and advanced centrifuges of various types." The Iranian announcement came after the IAEA's board on November 21 issued a second resolution condemning Tehran's cooperation with the agency after a similar warning in June. Some analysts say the resolution may be a step toward making a political decision to trigger a "snapback" of UN Security Council (UNSC) sanctions against Iran. The "snapback" mechanism is outlined in UNSC Resolution 2231, which enshrined a 2015 nuclear deal between Iran and world powers. However, the option to reimpose the sanctions expires in October 2025. The IAEA resolution, put forward by France, Germany, and Britain and supported by the United States, comes at a critical time as President-elect Donald Trump prepares to return at the White House in January. Trump during his first term embarked on a "maximum pressure" campaign of intensified sanctions on Iran and unilaterally withdrew the United States in 2018 from a landmark 2015 agreement that lifted some sanctions on Iran in exchange of curbs to its nuclear program, which the West suspects is aimed at obtaining a nuclear weapon. Iran claims its nuclear program is peaceful. The resolution passed on November 21 also urged Iran to cooperate with an investigation launched after uranium particles were found at two sites that Iranian authorities had not declared as nuclear locations. Nineteen of the 35 members of the IAEA board voted in favor of the resolution. Russia, China, and Burkina Faso opposed it, 12 members abstained, while one did not vote, diplomats who spoke on condition of anonymity told the AP. It also calls on the IAEA to come up with a "comprehensive report" on Iran's nuclear activities by spring. During Grossi's visit, Iran agreed with an IAEA demand to limit its stock of uranium enriched at 60 percent purity, which is still under the 90 percent threshold needed for a nuclear weapon, but it is much higher than the 3.67 percent limit it agreed to in the 2015 deal. However, Iranian Foreign Minister Abbas Araqchi, who was Tehran's chief negotiator for the 2015 agreement, warned that Iran would not negotiate "under pressure." Tehran has responded to previous similar resolutions by moves such as removing IAEA cameras and monitoring equipment from several nuclear sites, and increasing uranium enrichment to 60 percent purity at a second site, the Fordow plant. Two people were killed and 12 wounded in Russian strikes on Sumy early on November 22, Artem Kobzar, the mayor of the northeastern Ukrainian city, reported in a video statement on Telegram. "Several powerful explosions were heard in Sumy," he said in the video, adding that rescue teams, police, and ambulances were working at the site of the explosions. Kobzar urged residents to take shelter, saying that air defenses were still engaging incoming drones in the morning. Ukraine's air force said Russian drone attacks were under way in four regions -- Sumy, Kyiv, Chernihiv, and Zhytomyr. To read the original story by RFE/RL's Ukrainian Service, click here . A senior North Korean general has been wounded in Russia’s Kursk region, The Wall Street Journal reported, citing Western officials. More than 10,000 North Korean troops are supporting Russian forces in Kursk. Russian President Vladimir Putin is hoping to recover the swath of the Kursk region that Ukraine seized in August before President Donald Trump takes office early next year. The United States this week gave Ukraine the green light to use its long-range ATACMS missiles to strike Russian assets in Kursk and said North Korean troops would be fair game. It is unclear how the North Korean general was wounded, the WSJ reported . The United States has imposed sanctions on Gazprombank, Russia’s third-largest lender, and dozens of other financial institutions as President Joe Biden seeks to further curtail the Kremlin’s ability to finance its war in Ukraine before he leaves office in two months. Gazprombank, which plays an important role in facilitating Russian energy exports, was the only remaining large Russian lender not under U.S. sanctions. Washington and Brussels had avoided sanctioning Gazprombank amid concern over possible energy export interruptions. Along with Gazprombank, the United States also announced sanctions on more than 50 other Russian banks conducting international operations, more than 40 Russian securities registrars and 15 Russian finance officials. The United States also warned financial institutions against joining Russia’s version of the international messaging system for banks known as SWIFT. Russia is seeking to attract international banks to its messaging platform to get around U.S. financial sanctions. “Today’s action reaffirms the U.S. commitment to curtail Russia’s ability to use the international financial system to conduct its war against Ukraine and disrupts Russia’s attempts to make cross-border payments for dual-use goods and military materiel,” State Department spokesman Matthew Miller said in a November 21 statement. Ukraine backers had been calling on the Biden administration for months to tighten sanctions on Russia’s banking sector, saying the Kremlin was finding ways around existing sanctions to pay for technology imports and other dual-use items. In addition to facilitating energy payments, Gazprombank had been acting as a conduit for the purchase of military goods. The Kremlin also uses Gazprombank to pay Russian soldiers and compensate families for war deaths. “I am grateful to @POTUS and his administration for today’s strong package of financial and banking sanctions targeting Russia’s economy and war chest,” Ukrainian President Volodymyr Zelenskiy said in a tweet . Eddie Fishman, a former State Department official and sanctions expert, called the latest announcement a “strong step” toward closing loopholes around Russia’s energy sector, which generates about half of federal budget revenues. Biden will leave office on January 20 to make way for President-elect Donald Trump, who has promised to end the war in Ukraine by getting Zelenskiy and Russian President Vladimir Putin to sit down at the negotiating table, something that experts say will be harder done than said. The financial sanctions come at a critical time for Russia’s economy as Putin’s record spending on the war effort drives up inflation and interest rates. The Russian Central Bank last month raised interest rates to 21 percent, the highest in decades, and could continue to ratchet them up with no end in sight to the war. Russian President Vladimir Putin said his military fired a new intermediate-range missile into Ukraine following accusations by Kyiv that it was an intercontinental ballistic missile (ICBM). In a November 21 video statement to the nation, Putin said the use of the new weapon was a response to the United States and the United Kingdom giving permission to Kyiv to fire their long-range missiles into Russia. "In combat conditions, one of the newest Russian medium-range missile systems was tested," Putin said, adding that it was a hypersonic, ballistic missile capable of carrying a nuclear warhead. Earlier in the day, Kyiv accused Russia of striking Ukraine with what it said appeared to be an ICBM. The new weapon was part of a larger missile attack on Dnipropetrovsk, home to important military-industrial plants. ICBMs, which are designed to deliver long-distance nuclear strikes, have never been used in war before. "On the morning of November 21, 2024...Russian troops attacked the city of Dnipro (facilities and critical infrastructure) with missiles of various types. In particular, an intercontinental ballistic missile was launched from the Astrakhan region of the Russian Federation," the Ukrainian Air Force said in its statement on Telegram. Ukrainian President Volodymyr Zelenskiy said on Telegram later that the new Russian weapon had "all characteristics -- speed, altitude -- [of an] intercontinental ballistic missile." Pentagon spokeswoman Sabrina Singh said Russia struck Ukraine with an "experimental" intermediate-range ballistic missile that was based on its RS-26 Rubezh ICBM. She said Russia had informed the United States it would be launching the experimental missile shortly beforehand through "nuclear risk reduction channels." She said the new weapon had a smaller warhead that some other missiles Russia has launched into Ukraine. A U.S. official who asked not to be identified told media that Putin was seeking to intimidate Ukraine but added that Moscow only had a few of the "experimental" missiles. The Russian attack comes just days after reports that Ukraine used British-supplied Storm Shadow missiles and U.S.-made ATACMS systems to strike military targets deeper inside Russia following the long-sought approval by President Joe Biden. The RS-26 Rubezh is a solid-fueled, road-mobile ICBM currently in development that has been tested with heavier payloads at intermediate ranges. Military analysts said ICBM missiles can be classified as intermediate-range weapons when their payloads are increased and ranges decreased. The main target of the Russian attack was the southeastern region of Dnipropetrovsk, Ukraine's most important industrial region, and its capital, the city of Dnipro. Ukraine's air force said that besides the ICBM, Russian aircraft also launched a hypersonic Kh-47M2 Kinzhal missile and seven subsonic Kh-101 cruise missiles. Ukrainian air defenses shot down six Kh-101 missiles, the air force reported. Dnipropetrovsk Governor Serhiy Lysak said his region bore the brunt of the Russian attack. "Since early in the morning, the aggressor massively attacked our region," Lysak reported on Telegram, adding that preliminary information showed that an industrial facility was damaged in the regional capital, Dnipro, where two fires were started by the attack. Explosions were also reported in Kremenchuk, in the central Poltava region. Moscow's use of a large number of sophisticated missiles as opposed to the usual drone attacks appears to be in response to Ukraine's gaining approval to use some Western-donated long-range missile systems to strike deeper into Russia. On November 20, Russian military bloggers and a source cited by Reuters reported that Ukraine had fired up to 12 Franco-British Storm Shadow missiles into Russia's Kursk region, part of which has been under Ukrainian control following a surprise incursion by Ukrainian troops in August. A spokesman for British Prime Minister Keir Starmer declined to confirm whether the missiles had been used. Previously, London had given permission to use the Storm Shadows, which have a 250-kilometer range, within Ukraine's territory. Earlier this week, Ukraine reportedly used ATACMS to strike a military facility in Russia's Bryansk region after Biden was reported as giving his OK. The White House has not officially confirmed the approval and Ukraine hasn't directly acknowledged the use of ATACMS on Russian targets. Russia has long warned that Ukraine's use Western-supplied long-range weapons to strike inside its territory would mark a serious escalation of the conflict. On November 21, Moscow said a new U.S. missile defence base in the Polish town of Redzikowo near the Baltic coast, which was opened on November 13 as part of a broader NATO missile shield, will lead to an increase in the overall level of nuclear danger. "This is another frankly provocative step in a series of deeply destabilising actions by the Americans and their allies in the North Atlantic alliance in the strategic sphere," Russian Foreign Ministry spokeswoman Maria Zakharova said. "This leads to undermining strategic stability, increasing strategic risks and, as a result, to an increase in the overall level of nuclear danger," Zakharova said. Poland rejected the claim, saying there were no nuclear missiles at the base. "It is a base that serves the purpose of defense, not attack," Foreign Ministry spokesman Pawel Wronski said on November 21. At least 38 people were killed and more than 40 wounded after gunmen opened fire on a convoy of cars carrying Shi'ite Muslims in northwest Pakistan as religious tension in the region rises. Three women and a child were among those killed in the November 21 attack, police told RFE/RL's Radio Mashaal. The convoy of 200 cars was heading from Peshawar to Parachinar in Khyber Pakhtunkhwa Province near the border with Afghanistan when the unknown gunmen attacked. No one has taken responsibility for the attack, the latest in a series of deadly confrontations in the Kurram region. Police, who were escorting the cars, said the death toll could climb. There were about 700 people in the convoy, according to law enforcement. Tension in Kurram began to heat up after 17 people were killed in an attack on a convoy on October 12. There have been about a handful of deadly attacks since then. Sunnis and Shi'a live together in Kurram and have clashed violently over land, forests, and other property as well as religion over the years, despite government and law enforcement efforts to build peace. Influential Ukrainian tycoon Dmytro Firtash is among eight people targeted by fresh British sanctions that accuse the group, which includes his wife, Lada, of large-scale, international corruption. Angolan-Russian billionaire Isabel dos Santos and Latvian politician and businessman Aivars Lembergs are also among those hit by the new sanctions announced on November 21. The British government accuses Firtash of bribing officials to secure mining licenses for his companies and profiting illegally from Ukraine's gas-transportation system. Firtash is also linked to financier Denys Horbunenko, a resident of the United Kingdom who was added to the sanctions list on November 21 for his association with Firtash. Firtash has faced legal scrutiny in Ukraine over embezzlement and money-laundering accusations involving fraudulent gas-trading schemes. The United States has been seeking his extradition from Austria on charges of bribing Indian officials. Firtash, who gained prominence in the 2000s through his joint venture RosUkrEnergo with Russian energy giant Gazprom, has denied allegations of working in Russia's interests. Dos Santos, daughter of former Angolan President Jose Eduardo dos Santos, is Africa's first female billionaire. She is accused of corruption in Angola, where she allegedly exploited her political connections for personal gain. Dos Santos claims she has held Russian citizenship since birth, as she was born in Baku, Azerbaijan, in 1973 under the former Soviet Union. Lembergs, a former populist mayor of the Latvian city of Ventspils, has been convicted in Latvia of corruption and sentenced to five years in prison. He claims the charges against him are politically motivated. The sanctions are part of a British efforts to combat international corruption and disrupt the financial networks of individuals accused of abusing their power for personal enrichment. The measures include asset freezes, travel bans, and restricting these individuals from accessing the U.K.'s financial system or entering the country. The International Criminal Court (ICC) has issued arrest warrants for Israel's Prime Minister Benjamin Netanyahu and former Defense Minister Yoav Gallant, and Muhammad Deif, a military commander in the Iran-backed group Hamas, alleging they committed crimes against humanity in the ongoing Gaza war. All three are accused of committing war crimes connected to the October 7, 2023, attack on Israel by Hamas, an EU- and U.S-designated terrorist organization that is part of Tehran's network of proxies in the Middle East, and Israel's subsequent military intervention in the Gaza Strip. Iran's backing of Hamas and Hezbollah, another Iran-supported militant group and political party that controls much of the southern part of Israel's neighbor, Lebanon, has sparked fears that the war in the Gaza Strip will engulf the Middle East. Hezbollah is designated as a terrorist organization by the United States, while the European Union blacklists its armed wing but not its political party. Hezbollah’s political party has seats in the Lebanese parliament. The court said the warrants had been classified as "secret" to protect witnesses and to safeguard the conduct of the investigations. Israel, which claims it killed Deif in July, blasted the move as "a dark moment for the ICC." Hamas, which has never officially acknowledged Deif's death, called the warrants against Netanyahu and Gallant an "important step toward justice." The ICC said it had issued the arrest warrant for Deif as the prosecutor had not been able to determine whether he was dead. His warrant shows charges of mass killings during the October 7 attack on Israel that left some 1,200 dead, as well as charges of rape and the taking of around 240 hostages in the attack. "The Chamber considered that there are reasonable grounds to believe that both [Israeli] individuals intentionally and knowingly deprived the civilian population in Gaza of objects indispensable to their survival, including food, water, and medicine and medical supplies, as well as fuel and electricity, from at least 8 October 2023 to 20 May 2024," the ICC said in a statement . "This finding is based on the role of Mr. Netanyahu and Mr. Gallant in impeding humanitarian aid in violation of international humanitarian law and their failure to facilitate relief by all means at its disposal," it said. Israeli Foreign Minister Gideon Sa'ar called the move against Netanyahu and Gallant "absurd" in a post on X, saying it was an attack of Israel's right to self-defense. "A dark moment for the ICC in The Hague, in which it lost all legitimacy for its existence and activity," Sa'ar said. Tehran has yet to comment publicly on the warrants. Neither the United States nor Israel have recognized the ICC's jurisdiction. A U.S. National Security Council spokesperson said Washington "fundamentally rejects" the issuance of the arrest warrants and "the troubling process errors that led to this decision. Meanwhile, the EU's top diplomat, Josep Borrell, said in a post on X that ICC decisions "are binding on all states party to the Rome Statute, which includes all EU Member States." The court said Israel's acceptance of the court's jurisdiction was not required. However, the court itself has no law enforcement levers to enforce warrants and relies on cooperation from its member states. Russian police have conducted searches at the PERMM Museum of Contemporary Art in the city of Perm, as well as at the home of its current director, in connection with a case against former director Marat Gelman , REN-TV reported, citing anonymous sources. The PERMM Museum announced on social media that it would remain closed until 3 p.m. local time due to "technical reasons." Gelman, a well-known art dealer who currently lives in Montenegro, where he owns an art gallery, was placed on Russia’s federal wanted list in December 2022 under a criminal charge, though details of the accusation remain unclear. In an interview with Current Time, Gelman suggested that the charges might be in connection with him "discrediting" the Russian military, a common pretext used against critics of Russia's ongoing invasion of Ukraine. Gelman has been a vocal member of the Anti-War Committee and a member of the Permanent Committee of the Free Russia Forum. He has repeatedly expressed his support for Ukraine and his opposition to Russia's war efforts. The raid in Perm is part of a broader pattern of increasing pressure on Gelman. In the past week, he was added to Russia's list of "terrorists and extremists," with a designation indicating an ongoing criminal case against him. Critics argue this move is part of a crackdown on anti-war activists and dissenting voices within and beyond Russia. The Higher Public Prosecutor's Office in Novi Sad announced on November 21 that 11 people were arrested after being found responsible for the deadly collapse of a concrete canopy at the railway station in Serbia's second-largest city. The huge canopy collapsed on November 1, killing 15 people and seriously injuring another two. The accident occurred after the railway station, built in 1964, had been renovated twice in recent years by a consortium of four companies -- China Railway International and China Communications Construction, France's Egis, and Hungary's Utiber. Among those arrested are former Construction, Transport, and Infrastructure Minister Goran Vesic, and the ex-director of Railway Infrastructure, Jelena Tanaskovic. They face charges of committing criminal acts against public security, endangering the public, and irregular construction work, the prosecutor said in a statement, adding that they faced up to 12 years in prison. The arrests came after public protests that turned violent demanded the punishment of those responsible amid accusations of corruption that resulted in substandard renovation work on the railway station. In a message on X, Vesic wrote that he had not been arrested, but had "voluntarily responded to the call of the police officers" and "made himself available to police authorities." Vesic, an official from the ruling Serbian Progressive Party, resigned after the accident on November 4 but said he did not accept blame for the accident. Tomislav Momirovic, who headed the Construction, Transport, and Infrastructure Ministry from 2020 to 2022, submitted his resignation as trade minister on November 20. The same day, Tanaskovic resigned as head of Serbian Railway Infrastructure. Opposition politicians have voiced scepticism about the arrests and demanded that the case be handed over to organized-crime prosecutors. The office of Belarusian opposition leader Svyatlana Tsikhanouskaya has issued a statement condemning the recent extradition from Vietnam to Belarus of Vasil Verameychyk, who fought on the Ukrainian side against invading Russian troops. Verameychyk, who moved to Vietnam after he was denied permission to settle in Lithuania because of he had previously served in the Belarusian Army, was detained in Vietnam earlier this year. Despite international appeals, Vietnamese authorities proceeded with his extradition in late October 2024. Tsikhanouskaya's office described the extradition as a direct consequence of the repressive policies of the authoritarian ruler of Belarus, Alyaksandr Lukashenka, highlighting the regime's efforts to target opponents beyond its borders. The statement emphasizes the urgent need for stronger international mechanisms to protect human rights, not only for Belarusians fleeing repression but also for those supporting Ukraine in its efforts to repel Russia's ongoing invasion. It calls on the international community to adopt individualized approaches when reviewing cases for international protection, end cooperation with the Belarusian security forces, and suspend bilateral agreements on extradition and legal assistance with Belarus. Additionally, the statement advises Belarusians abroad to remain vigilant against potential actions by Lukashenka's security services. It recommends consulting resources like Pashpart.org to identify countries deemed unsafe for Belarusians at risk of persecution.Feeling the chill: Local heating companies facing uncertainty over state's upcoming Clean Heat Standard
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