sport betting prop firm Connor Clark & Lunn Investment Management Ltd. increased its holdings in shares of Castle Biosciences, Inc. ( NASDAQ:CSTL – Free Report ) by 147.4% during the third quarter, according to its most recent filing with the Securities & Exchange Commission. The firm owned 165,458 shares of the company’s stock after acquiring an additional 98,571 shares during the period. Connor Clark & Lunn Investment Management Ltd.’s holdings in Castle Biosciences were worth $4,719,000 as of its most recent SEC filing. Other institutional investors and hedge funds have also recently modified their holdings of the company. Vanguard Group Inc. grew its holdings in Castle Biosciences by 2.2% in the first quarter. Vanguard Group Inc. now owns 1,494,176 shares of the company’s stock valued at $33,096,000 after purchasing an additional 32,695 shares during the period. Harbor Capital Advisors Inc. lifted its position in shares of Castle Biosciences by 249.3% during the 2nd quarter. Harbor Capital Advisors Inc. now owns 138,707 shares of the company’s stock valued at $3,020,000 after buying an additional 99,001 shares in the last quarter. Lisanti Capital Growth LLC grew its stake in Castle Biosciences by 60.2% in the 3rd quarter. Lisanti Capital Growth LLC now owns 154,710 shares of the company’s stock valued at $4,412,000 after acquiring an additional 58,160 shares during the period. GSA Capital Partners LLP purchased a new stake in Castle Biosciences in the 3rd quarter worth $1,478,000. Finally, Principal Financial Group Inc. increased its holdings in Castle Biosciences by 2.7% in the 3rd quarter. Principal Financial Group Inc. now owns 1,538,520 shares of the company’s stock worth $43,879,000 after acquiring an additional 40,377 shares in the last quarter. Hedge funds and other institutional investors own 92.60% of the company’s stock. Insiders Place Their Bets In other Castle Biosciences news, CFO Frank Stokes sold 6,923 shares of Castle Biosciences stock in a transaction dated Friday, November 15th. The shares were sold at an average price of $29.93, for a total transaction of $207,205.39. Following the completion of the sale, the chief financial officer now directly owns 30,823 shares in the company, valued at $922,532.39. This trade represents a 18.34 % decrease in their ownership of the stock. The sale was disclosed in a legal filing with the Securities & Exchange Commission, which is available at the SEC website . Also, insider Derek J. Maetzold sold 986 shares of the business’s stock in a transaction that occurred on Friday, October 4th. The shares were sold at an average price of $28.73, for a total transaction of $28,327.78. Following the completion of the sale, the insider now directly owns 94,622 shares in the company, valued at $2,718,490.06. This trade represents a 1.03 % decrease in their ownership of the stock. The disclosure for this sale can be found here . Insiders sold a total of 24,213 shares of company stock valued at $752,673 over the last quarter. 7.20% of the stock is owned by insiders. Analyst Ratings Changes Read Our Latest Analysis on Castle Biosciences Castle Biosciences Stock Up 3.2 % Shares of NASDAQ:CSTL opened at $29.81 on Friday. Castle Biosciences, Inc. has a 52-week low of $16.97 and a 52-week high of $35.84. The company has a quick ratio of 7.64, a current ratio of 7.78 and a debt-to-equity ratio of 0.02. The business has a fifty day moving average of $30.98 and a two-hundred day moving average of $26.48. The stock has a market cap of $834.98 million, a P/E ratio of 149.06 and a beta of 0.99. Castle Biosciences ( NASDAQ:CSTL – Get Free Report ) last released its quarterly earnings data on Monday, November 4th. The company reported $0.08 earnings per share (EPS) for the quarter, topping the consensus estimate of ($0.06) by $0.14. The firm had revenue of $85.78 million during the quarter, compared to analysts’ expectations of $78.55 million. Castle Biosciences had a net margin of 1.95% and a return on equity of 1.47%. During the same period last year, the business earned ($0.26) earnings per share. On average, research analysts expect that Castle Biosciences, Inc. will post -0.08 earnings per share for the current year. Castle Biosciences Company Profile ( Free Report ) Castle Biosciences, Inc, a molecular diagnostics company, provides testing solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus, uveal melanoma, and mental health conditions. It offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test to identify the risk of metastasis for patients diagnosed with invasive cutaneous melanoma; DecisionDx-SCC, a proprietary risk stratification GEP test for patients with cutaneous squamous cell carcinoma; MyPath Melanoma, a test used for patients with difficult-to-diagnose melanocytic lesions; and TissueCypher, a spatial omics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, or low-grade dysplasia Barrett's esophagus. Featured Articles Want to see what other hedge funds are holding CSTL? Visit HoldingsChannel.com to get the latest 13F filings and insider trades for Castle Biosciences, Inc. ( NASDAQ:CSTL – Free Report ). Receive News & Ratings for Castle Biosciences Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Castle Biosciences and related companies with MarketBeat.com's FREE daily email newsletter .

As Lin Jing'en faded into the background, her legacy as the female lead of the controversial film "Grandfather-Granddaughter Love" lived on. The film, once a source of fame and controversy for the actress, now stood as a reminder of a bygone era, a time when Lin Jing'en was at the peak of her career.As Henan seeks opinions on this proposal, it is crucial for stakeholders to carefully consider the potential benefits and drawbacks of the policy change. Balancing the interests of homeowners, developers, and the government is key to ensuring that any decision made brings about positive outcomes for all parties involved.In addition to their internal preparation, Atlanta United must also be mindful of their competition in the league. Tachnadi is home to many strong and talented teams who are also vying for the championship title. Understanding their opponents' strengths and weaknesses, adapting their tactics accordingly, and maintaining a competitive edge will be essential for Atlanta United to stay ahead in the race for the title.

As Son Heung-Min continues to work hard and strive for excellence, his determination and passion for the game set him apart as a true professional. With the backing of Mauricio Pochettino and his teammates, Son has the support and encouragement he needs to overcome challenges and reach new heights in his career.

Samsung T7 SSDs Are 50% Off Post Black Friday, Amazon Has Lost Its Mind AgainThe CEO of United Health, a prominent figure in the healthcare sector, was targeted by the assailant while leaving a corporate event in downtown New York City. The assailant, armed with a handgun, attempted to shoot the CEO at close range before being apprehended by security personnel.

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HARRISBURG — Democratic Sen. Bob Casey of Pennsylvania conceded his reelection bid to Republican David McCormick on Thursday, as a statewide recount showed no signs of closing the gap and his campaign suffered repeated blows in court in its effort to get potentially favorable ballots counted. Casey’s concession comes more than two weeks after Election Day, as a grindingly slow ballot-counting process became a spectacle of hours-long election board meetings, social media outrage, lawsuits and accusations that some county officials were openly flouting the law. Republicans had been claiming that Democrats were trying to steal McCormick’s seat by counting “illegal votes.” Casey’s campaign had accused of Republicans of trying to block enough votes to prevent him from pulling ahead and winning. In a statement, Casey said he had just called McCormick to congratulate him. “As the first count of ballots is completed, Pennsylvanians can move forward with the knowledge that their voices were heard, whether their vote was the first to be counted or the last," Casey said. The Associated Press called the race for McCormick on Nov. 7, concluding that not enough ballots remained to be counted in areas Casey was winning for him to take the lead. As of Thursday, McCormick led by about 16,000 votes out of almost 7 million ballots counted. That was well within the 0.5% margin threshold to trigger an automatic statewide recount under Pennsylvania law. But no election official expected a recount to change more than a couple hundred votes or so, and Pennsylvania's highest court dealt him a blow when it refused entreaties to allow counties to count mail-in ballots that lacked a correct handwritten date on the return envelope. Republicans will have a 53-47 majority next year in the U.S. Senate. Turkey with a side of politics? No thank you. As Thanksgiving approaches, so does the challenge of navigating political discussions with relatives. Here are some quick tips to make your Thanksgiving more enjoyable. Veuer’s Maria Mercedes Galuppo has the story. Stay up-to-date on the latest in local and national government and political topics with our newsletter.

As tensions escalated, the woman insisted that the man show her his phone to verify that he had not captured any unauthorized footage. Reluctantly, the man handed over his phone for inspection, which revealed a series of recent photographs taken in the mall. The woman's suspicions were heightened as she observed that some of the photos appeared to have been taken surreptitiously, with shots of her and other unsuspecting individuals.

No. 6 Purdue routs Marshall

OPTA Latest Team Strength Ranking: Liverpool Tops the List, Inter Milan in Second Place, Manchester City, Real Madrid, and Juventus in Third to FifthFurthermore, a U.S. withdrawal from NATO would have broader geopolitical ramifications, affecting not only transatlantic relations but also global security dynamics. The alliance plays a pivotal role in shaping the strategic environment and promoting democratic values and principles worldwide. An American retreat from NATO could signal a retreat from its leadership role in maintaining international order and upholding democratic norms, leaving a void that could be exploited by authoritarian regimes and hostile actors.

If you find yourself experiencing persistent fatigue, mood changes, or difficulty concentrating, it may be time to reassess your sleep habits. Rather than dismissing these symptoms as normal parts of a busy life, consider them as valuable warning signals from your body. By listening to what your body is telling you and addressing the root cause of your sleep deprivation, you can take proactive steps towards improving your quality of life.In response to the mishap, the Village Committee has announced a series of measures aimed at preventing similar incidents in the future. Firstly, all drones used in public displays will undergo rigorous testing and certification to ensure their reliability and resistance to signal interference. Additionally, the committee plans to implement stricter guidelines for drone operators, including mandatory training on handling emergency situations and signal disruptions.None

ENGLEWOOD, Colo. (AP) — John Elway says any remorse over bypassing Josh Allen in the 2018 NFL draft is quickly dissipating with rookie Bo Nix's rapid rise, suggesting the Denver Broncos have finally found their next franchise quarterback. Elway said Nix, the sixth passer selected in April's draft, is an ideal fit in Denver with coach Sean Payton navigating his transition to the pros and Vance Joseph's defense serving as a pressure release valve for the former Oregon QB. “We’ve seen the progression of Bo in continuing to get better and better each week and Sean giving him more each week and trusting him more and more to where last week we saw his best game of the year,” Elway said in a nod to Nix's first game with 300 yards and four touchdown throws in a rout of Atlanta. For that performance, Nix earned his second straight NFL Rookie of the Week honor along with the AFC Offensive Player of the Week award. “I think the sky’s the limit," Elway said, “and that’s just going to continue to get better and better.” In a wide-ranging interview with The Associated Press, Elway also touted former coach Mike Shanahan's Hall of Fame credentials, spoke about the future of University of Colorado star and Heisman favorite Travis Hunter and discussed his ongoing bout with a chronic hand condition. Elway spent the last half of his decade as the Broncos’ GM in a futile search for a worthy successor to Peyton Manning, a pursuit that continued as he transitioned into a two-year consultant role that ended after the 2022 season. “You have all these young quarterbacks and you look at the ones that make it and the ones that don’t and it’s so important to have the right system and a coach that really knows how to tutelage quarterbacks, and Sean’s really good at that,” Elway said. “I think the combination of Bo’s maturity, having started 61 games in college, his athletic ability and his knowledge of the game has been such a tremendous help for him,'" Elway added. “But also Vance Joseph’s done a heck of a job on the defensive side to where all that pressure’s not being put on Bo and the offense to score all the time.” Payton and his staff have methodically expanded Nix’s repertoire and incorporated his speed into their blueprints. Elway lauded them for “what they’re doing offensively and how they’re breaking Bo into the NFL because it’s a huge jump and I think patience is something that goes a long way in the NFL when it comes down to quarterbacks.” Elway said he hopes to sit down with Nix at some point when things slow down for the rookie. Nix, whose six wins are one more than Elway had as a rookie, said he looks forward to meeting the man who won two Super Bowls during his Hall of Fame playing career and another from the front office. “He’s a legend not only here for this organization, but for the entire NFL," Nix said, adding, "most guys, they would love to have a chat with John Elway, just pick his brain. It’s just awesome that I’m even in that situation.” Orange Crush linebacker Randy Gradishar joined Elway in the Pro Football Hall of Fame this year, something Elway called “way, way overdue.” Elway suggested it's also long past time for the Hall to honor Shanahan, who won back-to-back Super Bowls in Denver with Elway at QB and whose footprint you see every weekend in the NFL because of his expansive coaching tree. Elway called University of Colorado stars Travis Hunter and Shedeur Sanders “both great athletes." He said he really hopes Sanders gets drafted by a team that will bring him along like the Broncos have done with Nix and he sees Hunter being able to play both ways in the pros but not full time. Elway said he thinks Hunter will be primarily a corner in the NFL but with significant contributions on offense: “He's great at both. He's got great instincts, and that's what you need at corner." It's been five years since Elway announced he was dealing with Dupuytren’s contracture, a chronic condition that typically appears after age 40 and causes one or more fingers to permanently bend toward the palm. Elway's ring fingers on both hands were originally affected and he said now the middle finger on his right hand is starting to pull forward. So, he’ll get another injection of a drug called Xiaflex, which is the only FDA-approved non-surgical treatment, one that he's endorsing in an awareness campaign for the chronic condition that affects 17 million Americans. The condition can make it difficult to do everyday tasks such as shaking hands or picking up a coffee mug. Elway said what bothered him most was “I couldn't pick up a football and I could not imagine not being able to put my hand around a football." AP NFL: https://apnews.com/hub/nflFor Manchester United, the decision to sell Rashford would not be taken lightly. The club hierarchy recognizes Rashford's status as a homegrown talent and a fan favorite, and selling him would undoubtedly be a controversial move. However, with the need to strengthen other areas of the squad and the emergence of promising young talents, the club may see this as a necessary step in order to move forward and compete at the highest level.None

SANTA CLARA — Brock Purdy is charged with distributing the ball to the 49ers’ still-plentiful array of offensive weapons. On Tuesday, he threw disgruntled wide receiver Deebo Samuel his full support. “I want to get Deebo the ball every play if I could,” Purdy said. “I want to have him break all the records as best as possible. I want Deebo to do Deebo things, and we all do in this building.” Thing is, Samuel’s sub-par production this season has mirrored the 49ers’ rocky road to a 6-7 record entering Thursday night’s visit by the Rams (7-6). “Not struggling at all just not getting the ball!!!!!!!” Samuel wrote Monday in a since-deleted post on the social media platform X. The timing off that complaint was peculiar. The 49ers had just shaken a three-game losing streak with a 38-13 win over the Chicago Bears, a game Samuel acknowledged was their best offensive showing and most complementary outing. But the 49ers did so with minimal production again from Samuel, who had two catches for 22 yards and five carries for 13 yards. “You read what you read. A little frustrated, for sure,” Samuel said Tuesday at his locker before practice. General manager John Lynch asked 49ers fans to give Samuel “some grace,” and coach Kyle Shanahan also threw support behind Samuel’s gripes. “Deebo and I talk every day so I understand Deebo saying that,” Shanahan said. “Deebo wants to help us out, and the only way he is helping us is getting the ball more. And we’d like to get him the ball more.” Samuel, a two-time captain, has scored just two touchdowns (Week 1 run, Week 5 reception) after 12 last regular season; he had 14 in 2021. He missed the 49ers’ Week 3 loss in Los Angeles because of a calf injury. Three years removed from his All-Pro breakout season, Samuel’s production has taken a nosedive this season, even though he is getting the ball. His 72 touches (40 receptions for 533 yards, 32 carries for 92 yards) are second to only now-injured running back Jordan Mason’s 164. In an X post 10 minutes after complaining about his opportunities, Samuel wrote : “Just cause I voice my opinions don’t mean I’m hating on any of my teammates!!” Jauan Jennings (57 catches, 774 yards, six touchdowns) and tight end George Kittle (56-800-8) have seized more on their targets from Brock Purdy, while 2022-23 mainstays Brandon Aiyuk and Christian McCaffrey have missed most of the season injured. “We’d always love things to stay in-house,” Shanahan said. “It’s probably why I don’t go on social media: I’d get worked up if I was reading stuff all the time. Is it a distraction in our building? No.” “He’s one of my best friends on this team. I absolutely love Deebo and what he’s done for me,” Purdy said. “He’s right: he’s doing great right now with what we ask of him the offense. He’s not struggling. Like Ricky (Pearsall) or Aiyuk last year a little bit, there are moments through a season where guys just don’t get the ball, depending on defensive schemes and taking guys away.” Samuel has flourished in the 49ers’ rivalry against the Rams, including three years ago when his “wide back” persona emerged as he scored on both a run and a reception to lead the victorious 49ers out of a 3-5 rut and toward the playoffs. That dual-threat duty is not such an inventive concept anymore, however. “They’re not surprised anymore,” Samuel said. “We’ve been doing it almost three years now, so you’ve got a 50-50 chance whether I’m in the backfield getting a handoff or anything along those lines. They have a glimpse of what’s going on. ... There’s three or four (defenders awaiting) no matter who has the ball.” “Deebo has created such a high standard, the things he’s done, the innovation which we’ve created things for Deebo. That’s part of the problem,” said Lynch, noting that multiple teams now deploy Samuel-esque, dual-threat players that no longer surprise defenses. “... That frustration mounts. But he’s made so many plays for us, I think we need to give this guy some grace and bring him along, because we need him the rest of the way,” Lynch added. “We need him Thursday night. Deebo’s a big part of this team. We’re alright. We can all learn from different situations and a lot of things in the world these days that you can get caught up in.” Some of Samuel’s most productive efforts this season have come as a kick returner (11 returns for 333 yards, including six returns in their Dec. 1 loss at Buffalo). “We’ve got a lot of big football to play and he’ll be a big part of our season moving forward,” Lynch said. As for next season, Samuel carries a $16 million mark on the salary cap. The 49ers restructured his contract in March, so he would incur a $31.6 million hit if he’s released or traded before June 1; after that date, an exit would count $11 million in 2025 and $21 million in ’26. GUERENDO IDLING Running back Isaac Guerendo’s foot sprain Sunday kept him out of Tuesday’s light walkthrough and it’s uncertain whether he’ll make a second straight start. Guerendo ran for 78 yards and two touchdowns, and he had 50 yards on two catches, before exiting and bequeathing the backfield to Patrick Taylor Jr. Guerendo got clocked at 20.2 mph on a 30-yard, second-quarter carry that was the NFL’s fastest by a running back in Week 14. GREENLAW UPDATE The 49ers remain reluctant to declare whether linebacker Dre Greenlaw will make his season debut Thursday night, the date pegged for his comeback from an Achilles tear in the Super Bowl. Shanahan said there’s been no setback, that he merely wants to talk first to Greenlaw and see how the next two days go. OTHER INJURY UPDATES Defensive end Nick Bosa (oblique, hip) and left tackle Trent Williams (ankle) will officially miss the fourth week of practice, albeit this week’s only consisting of Tuesday’s walk-through that began at 5:10 p.m. Shanahan has not indicated whether they’ll miss a fourth straight game. While left guard Aaron Banks practiced for the first time since a Nov. 24 concussion in Green Bay, guard Ben Bartch (ankle) did not practice and is expected to go on Injured Reserve before Thursday’s kickoff. Limited were defensive end Yetur Gross-Matos, safety Malik Mustapha, and linebackers Dee Winters and Demetrius Flannigan-Fowles. HARGRAVE MOVEMENT Defensive tackle Javon Hargrave’s bloated contract was restructured to lessen the 49ers’ financial restraints next year. While that could stage his potential release after two seasons, as pointed out by OverTheCap.com, Hargrave is also more affordable to keep, seeing how his 2025 salary was chopped from $19.9 million to $2.1 million, and his salary cap mark fell from $28 million to $10.3 million. “The plan for him is to be a Niner,” Shanahan said, deferring business matters to the front office staff. “The mechanics of contract stuff, those are things I don’t look into until after the offseason.” Hargrave, 31, has been on injured reserve since tearing a biceps in the Sept. 22 loss at Los Angeles. He made the Pro Bowl last season and totaled seven sacks in his first year with the 49ers. Jordan Elliott replaced him in this season’s lineup next to Maliek Collins, with rookie Evan Anderson, Kevin Givens, Kalia Davis and Khalil Davis also in the interior rotation.Companies must also uphold ethical standards and prioritize honesty and integrity in their business practices. Short-term gains achieved through deception or infringement can have long-lasting repercussions on a company's reputation and legal standing. By fostering a culture of compliance and ethical conduct, businesses can build trust with consumers and contribute to a sustainable and responsible industry environment.Seyi Tinubu: Strong PDP chieftain reveals how party members sign secret deals with APC

KPCC needs a full-time president: Satish JarkiholiMeet The Parents 4 slammed by fans as Robert De Niro and Ben Stiller reunite for sequel: 'Nobody needs this'

Ferdinand Ekechukwu American tech conglomerate, Meta, recently hosted its first Youth Summit in Lagos, bringing together over 200 young professionals, students, fresh graduates, creatives, tech enthusiasts and aspiring entrepreneurs in a fun and interactive atmosphere, making best memories and connecting with the young Nigerians. With 70 per cent of Nigeria’s population under age 30, young and vibrant, Meta appreciates and understands that, hence the need for engaging every one of the attendees. The summit, essentially, was birthed out of the need to take advantage of the energy of that vibrant, young population of Nigerians and opening up a world of possibilities. Themed ‘Empowering Youth Through Technology, Innovation and Entrepreneurship’, the summit included a series of thought-provoking panel discussions, a mentoring session and an interactive workshop designed to equip young Nigerians with the skills, insights and networks needed to thrive in today’s tech-driven world. Commenting about the event, Phil Oduor, Head of Policy Programmes, Sub-Saharan Africa said, “At Meta, we believe that today’s youth are tomorrow’s change-makers. Through initiatives like the Youth Summit, we aim to foster innovation, promote digital literacy and empower young Nigerians with the tools and opportunities to realise their potential and contribute to Nigeria’s growing digital economy.” Delivering the keynote address, Femi Aluko, CEO/Co-Founder, Chowdeck, shared his journey of breaking barriers to achieve success in tech. He encouraged attendees to embrace the limitless opportunities within today’s technology ecosystem.”Keep working, keep moving and the winning will come” Aluko charged the audience. A panel discussion, led by Chinny Francis, Public Policy Manager at Meta, titled ‘The Future of Work: Thriving in a Digitally Transformed World’ featured panelists Nifemi Akinwamide, Head of Operations, Alt School; Adaora Mbelu, Co-Founder of Lumination Global and Obaloluwa Adeagbo, Marketing Lead at Talstack. They shared valuable insights about the future of work, emphasising the importance of storytelling to build a personal brand, practicing self-awareness, developing soft skills, lifelong learning and honing problem-solving skills to thrive in a digitally transformed world. Technical Adviser for Innovation, Entrepreneurship and Capital at the Federal Ministry of Communications, Innovation and Digital Economy, Francis Sani, spoke at the event. He highlighted the 3 Million Technical Talent (3MTT) programme, emphasising that the programme aims to build Nigeria’s technical talent backbone to drive the digital economy and position Nigeria as a net talent exporter. He encouraged youth to take advantage of this opportunity. Another panel of industry experts took the stage during the ‘Lunch and Learn: Navigating Entrepreneurship in a Rapidly Changing Landscape’ session, moderated by Sade Dada, Head of Public Policy for Anglophone West Africa at Meta. Seye Bandele, CEO of PaidHR and Damilola Teidi-Ayoola, Head of Platform and Networks at Ventures Platform Fund, shared their invaluable insights. Seye highlighted the importance of grit, curiosity and candour, while Damilola reinforced the need to understand one’s target audience, deliver value through their business and embrace data-driven decision-making in the dynamic entrepreneurial landscape. The event also featured vibrant and inspiring conversations with leading figures in the creative industry. Miss Techy, an award-winning tech content creator and Salem King, a creator, storyteller, author and speaker, shared their experiences and advice on achieving long-term success. Attendees also benefited from an interactive workshop and a mentoring session, where industry experts shared practical advice and strategies for entrepreneurs and tech enthusiasts. Meta’s Youth Summit 2024 highlights a commitment to driving positive change, championing youth empowerment and advancing economic opportunities in Nigeria. Through investments in key areas—such as the creative industry, digital literacy, economic impact and youth job training—Meta is dedicated to empowering young Nigerians to thrive in today’s tech-driven world. The aim is to foster innovation, promote digital literacy and empower young Nigerians with the tools and opportunities to realise their potential and contribute to Nigeria’s growing digital economy.Union Minister Manohar Lal Khattar flags off NTPC’s green hydrogen buses