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Under a canopy of eight heart-monitoring screens in a cardiac catheterization lab on a recent Monday, Mayo Clinic doctors briefly paused a procedure treating atrial fibrillation to inspect a new tool: a long tube with what looked like flower petals made out of wire at its end. That wiry flower is the focus of a multibillion-dollar innovation race between some of the world’s largest medical technology companies. Medtronic and Boston Scientific, which both have major cardiac-device operations in Minnesota, and Johnson & Johnson MedTech are vying to control the large and fast-growing market for minimally invasive medical devices to treat the widespread heart problem atrial fibrillation with a safer and quicker procedure called pulsed field ablation (PFA). PFA uses electric pulses instead of extreme heat or cooling to ablate cardiac tissue around pulmonary veins on the heart, blocking bioelectric signals in the tissue that cause the heart’s atrial chambers to quiver, or fibrillate. Atrial fibrillation, or AFib, is believed to affect more than 10 million Americans, greatly increasing their risk of having a stroke, the latest scientific estimates show. Doctors say the new ablation procedure cuts down a patient’s time in the cath lab by hours, and reduces risks for serious complications compared to older techniques. Medtech executives expect the technology to help fuel their companies’ future growth. Boston Scientific CEO Mike Mahoney has said the company’s new Farapulse ablation system is “the most transformational product that I’ve seen in my career.” Medtronic CEO Geoff Martha has said, “We’re at one of those moments in medtech where a new technology is causing a rapid shift in the treatment of a disease. In this case, PFA is that technology.” Analytics company Clarivate projects pulsed field ablation devices will surpass $1.3 billion in sales globally this year, and the total number of procedures performed will at least quadruple in the next two to three years as PFA makes up an increasingly large share of all ablations performed. The Farapulse system was first to market in Europe, gaining regulatory approval in early 2021, before Boston Scientific acquired it later that year. The U.S. Food and Drug Administration then approved Medtronic’s system, called PulseSelect, last December. Then Farapulse, which includes hardware built in Minnesota, received FDA approval in January. Johnson & Johnson MedTech also received FDA approval for its Varipulse system earlier this month. The companies are now pushing to commercialize premium PFA systems that map the heart and reduce incisions into the body as the technology floods hospitals. Tony Crisci of Ocean City, N.J., said he held off for a procedure at Mount Sinai in New York until the new technology became available. “I thought I was just getting older, and I couldn’t work out as hard [without getting] out of breath,” Crisci, 67, said of his condition before he received treatment with Boston Scientific’s system. “But now I feel like 20 years younger.” In the Mayo Clinic heart-catheterization lab, a patient was on the table swarmed by health care professionals, wires and massive devices that made the room look like the inside of a spacecraft by roughly 8:30 one recent morning. The ablation wrapped up by 10:30 a.m. That’s not how quickly AFib procedures formerly went. Older radiofrequency ablation tools use heat, taking minutes for each round of ablation near the pulmonary vein. During PFA, each electric pulse is delivered in a matter of nanoseconds during a secondslong delivery window, reducing the procedure’s time by hours. Mapping and monitoring the heart seemed to take longer than the ablation during the Mayo Clinic procedure. AFib is an irregular heart rhythm when the heart’s upper chambers chaotically beat out of sync with the lower chambers, increasing risk of stroke and heart failure. Mayo Electrophysiology laboratory director Dr. Suraj Kapa said incidence of the arrhythmia is expected to increase as the population becomes older and the world faces an obesity epidemic. Common symptoms include a racing or fluttering heart, lightheadedness, chest pain and extreme fatigue, but some patients have no symptoms: “It can range from somebody being totally asymptomatic — they don’t feel it at all — all the way to somebody feeling essentially like a truck ran them over,” Kapa said. Crisci, who had a PFA procedure at Mount Sinai, said he felt short of breath whenever he exerted himself in recent years. A doctor discovered his AFib during a routine physical in 2022. Patients can control AFib through medications or ablation procedures, but there’s no true cure. Dr. Khaldoun Tarakji, chief medical officer of Medtronic’s cardiac ablation unit, said anti-arrhythmic drugs can cause potentially fatal side effects. Boston Scientific Chief Medical Officer Dr. Ken Stein said drugs are often ineffective. “Even a decade ago,” Stein said, “it was clear that some type of ablation procedure was ultimately going to be preferred versus drugs for patients.” Pulsed field ablation is at least as effective and is certainly more efficient than conventional thermal ablation, which includes radiofrequency and cryoablation methods, Stein said. During a cryoablation procedure, a balloon expands inside a pulmonary vein, freezing tissue with extreme cold, said Dr. Henri Roukoz, director of electrophysiology at the University of Minnesota Medical Center. Radiofrequency ablation, which is more common, cauterizes tissue around the pulmonary vein point by point, in intervals that take minutes and add up to hours. Using thermal sources, doctors can inadvertently damage other organs like the esophagus, leading to rare but potentially fatal complications, Roukoz said. Pulsed field ablation uses a high voltage impulse to create pores in cells in the area surrounding the pulmonary vein, causing them to disintegrate and die, doctors said. Because the pulses are localized to targeted cells, doctors said there’s a smaller chance the procedure affects adjacent organs. Crisci said physicians offered him drugs or ablation but he declined long-term medication for treatment: “I don’t take aspirin or anything.” He said he held off on the procedure until he landed a spot in Johnson & Johnson MedTech’s clinical trial. In the Mayo Clinic cath lab, Dr. Peter Noseworthy and Dr. Robert Ward made two incisions on the left and right side of the patient’s groin to insert catheters, which are thin tube-shaped devices physicians can advance to the heart through blood vessels, allowing access to the heart without open surgery. The doctors threaded a mapping catheter — with several tiny legs sprouting from its end — through the groin, moving it up blood vessels until it reached the heart. There, its metallic legs danced across the interior surface of the heart as the physician toggled the device’s controller. This produced a model of the heart that allowed the physicians to precisely identify spots for ablation. Then the physicians threaded a Farapulse catheter into the right incision and snaked it toward the heart. They poked a hole in the heart’s interior so the catheter could move from the right upper chamber to the left upper chamber, which the arrhythmia affects. The doctors delivered roughly eight electric pulses to the heart. Each pulse gets delivered after the tap of an iPad-like touchscreen. The procedure wraps up quickly. It’s at least as effective as radiofrequency ablation, but the arrhythmia can return, doctors say. Crisci said he healed quickly following his first ablation in March using the J & J technology, but he went back into AFib about a week and a half later. He received a second procedure in July, and he said he hasn’t had AFib since. Now, he’s hitting the gym more. “It’s really giving me a second youth,” Crisci said. At the electrophysiology divisions of the biggest medtech companies, executives spotted the promising market years ago. Boston Scientific acquired University of Iowa startup Farapulse in 2021 for hundreds of millions of dollars after first investing in the company in 2014. In 2022, Medtronic acquired Affera, the company behind its new catheter that ablates and maps the heart, for $925 million. Stein said physicians use Farapulse in the large majority of pulsed field procedures. Its Minnesota-based division within Boston Scientific grew by 177% on an organic basis during the most recent quarter. Jasmina Brooks, president of Johnson & Johnson MedTech’s electrophysiology division, said the company’s pulsed field system was the first in the U.S. to fully integrate with the company’s 3D heart-mapping system, which helps doctors visualize the heart as they position the catheter and deliver the energy. And Tarakji of Medtronic said the adoption of PFA “has even exceeded the wildest expectation.” With PulseSelect, he said patients often don’t experience some of the side effects of radiofrequency ablation like chest pain. He pointed out that that the company’s catheter has one of the smallest diameters, which can reduce recovery time. The race doesn’t come without obstacles. A supplier problem held back Medtronic PulseSelect sales for the most recent reported quarter. Boston Scientific paused an important clinical trial to expand the use of its technology as a first-line treatment for persistent AFib after making unanticipated observations — and then restarted it weeks later. The companies are now incorporating mapping technology into the ablating catheter to further streamline the procedure. And Tarakji said Medtronic is in early feasibility studies to study whether the company’s technology can treat a serious arrhythmia called ventricular tachycardia. Nick Spadea-Anello, president of Boston Scientific’s electrophysiology division, said the the new technology will fuel future innovation. Said Stein: “The potential now is to offer them ... a therapy that is safe, a therapy that’s effective and a therapy that is efficient for the system as a whole: It just changes patients’ lives.”abrdn Emerging Markets Equity Income Fund, Inc. (AEF) Announces Results Of Strategic Review Including: Changes To The Fund’s Name And Investment Strategy, A 20% Tender Offer And Renewed Performance-based Conditional Tender Offer Policy, And An Increase To Managed Distribution Policy

( MENAFN - GetNews) On December 6th, nine groundbreaking AI-generated short films were unveiled in China. This exciting project brought together some of the country's most celebrated filmmakers, including Jia Zhangke, winner of the Lifetime Achievement Award at Cannes, and Timmy Yip, who won an Academy Award for his work on Crouching Tiger, Hidden Dragon. These nine experimental short films, which explore genres like fantasy, folklore, family drama, and animation, were all created using Kling AI 's powerful video generation tool. Ranging from three to six minutes long, the films showcase a fusion of AI technology and traditional filmmaking techniques, marking a historic first in global cinema. "AI gives us boundless imagination... you can go anywhere you want," said Yip, who won the 20th Best Art Direction and Best Costume Design Awards for his work on Crouching Tiger, Hidden Dragon in 2001. In Yip's AI short film The Courier, he depicts a novel space world where an alien courier, Lili, embarks on a quest to awaken the Earth in search of the Silver Dragon. The mottled surface of the Earth, the dust stirred up by the rapid landing of the spacecraft, every frame of the realistic imagery immerses viewers in the experience. As Lili's adventure unfolds, it gradually reveals the Earth's decay and potential for revival, reflecting profound contemplation on life existence, and the future. Yip was particularly amazed by the AI's ability to create an alien character with human-like traits. "I found it quite fun," he said, "the alien looks at you, blinks, and feels somewhat familiar-almost like it has a human touch, which was surprising." Shi Shuo, an AIGC application engineer involved in The Courier, explained that he extensively used functions like frame control in his creation. Shi believes that "A truly great AI tool should provide creative inspiration while also allowing for deep control over the process. Kling AI has exceeded expectations in this regard." In addition, Kling AI is equally adept at tension-filled picture expression through the form of animation. Among the nine AI-produced movies, the well-known Chinese animation director Wang Maomao's Till Next Time, Bunny tells the story of a boy's panic and helplessness due to his failing examination paper in the form of animation, which is eventually released because of his family's love and care. The giant monster and the endless ladder in the film are all visualizations of the boy's inner pressure. In Wang 's opinion,“Animation is the most suitable form of creation to utilize imagination, and the addition of AI brings more ways of expression.” Since Sora's stunning debut earlier this year, demonstrating cutting-edge AI generated video technology, large video models have sprung up globally. Despite officially launching in June, Kling AI has garnered significant attention for its rapid growth and innovation, quickly stood out as a leader in the field of global video large models. According to data from the authoritative website analysis tool Similarweb, among many AI video products of the same period, Kling AI's traffic growth has been extremely rapid. As of September 24th, Kling AI's total visits had climbed to 33.7 million, surpassing the already released products Runway (31.34 million) and Pika (7.52 million). Zhang Di, Vice President of Kuaishou Technology and head of the large model team, introduced that since its release this year, Kling AI has maintained a high-speed iteration, achieving significant progress in model quality, aesthetic performance, control capabilities, and other aspects. It now has more than 5 million users, generating over 51 million videos and over 150 million images. “The nine AIGC short films not only highlight Kling AI's extraordinary ability to simulate the physical world and create unique visual effects,” Zhang Di explained,“but they also embody the directors' open-minded approach to new technologies and their willingness to embrace innovative creative methods.” Jia Zhangke, a giant in Chinese cinema, also embraced AI in his short film Wheat Harvest. Known for his thought-provoking storytelling, Jia used Kling AI to experiment with new creative possibilities. He previously won the Best Screenplay Award at the 66th Cannes International Film Festival for his film A Touch of Sin. In 2015, he received the Lifetime Achievement Award at the Director's Fortnight of the 68th Cannes International Film Festival. Jia introduced that he has always been curious to the development of AI. In his work Wheat Harvest, he first tried and explored the possibilities of Kling AI in film creation. The entire AIGC movie short uses the traditional cinematic narrative approach as well as the split-screen method of a road movie to create more application scenarios through AI. In just six minutes, Kling AI can achieve multiple space transitions and the continuous presence of characters, "which is a great surprise." Nonetheless, Jia also frankly stated that he hopes to explore the possibilities of AI itself using Kling AI. "I may not shy away from the fact that Kling needs to be improved in its current development stage, or the challenges that AI technology as a whole faces. I think that only if we creators, working together with scientists and technologists, touch that boundary together, and we create more application scenarios, AI can develop more rapidly." 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Better AI Stock: Nvidia vs. Palantir?US Appeals to Rebel Group for Austin Tice's Release2024 in pop culture: In a bruising year, we sought out fantasy, escapism — and cute little animals

Atalanta 2-3 Real Madrid: Highlights, man of the match, stats as Los Blancos survive late scare to claim vital away winPV Sindhu and Venkata Datta Sai (X Photo) Olympic badminton star PV Sindhu recently tied the knot to entrepreneur Venkata Datta Sai . The private ceremony took place in Udaipur. Sindhu, a two-time Olympic medalist, is 29 years old and hails from Hyderabad. Her impressive career includes a bronze medal at the 2016 Rio Olympics and a silver at the 2020 Tokyo Olympics. The groom, Venkata Datta Sai, is an executive director at Posidex Technologies. PV Sindhu delighted fans with her wedding pictures. The wedding took place on Sunday, adhering to traditional customs, and was attended by close family and friends. Union Minister of Culture and Tourism, Gajendra Singh Shekhawat, shared the first official wedding photo on 'X', formerly known as Twitter, the following Monday. “Pleased to have attended the wedding ceremony of our Badminton Champion Olympian PV Sindhu with Venkatta Datta Sai in Udaipur last evening and conveyed my wishes & blessings to the couple for their new life ahead.” The wedding festivities commenced with a vibrant Sangeet ceremony on December 20th. The event featured music and dance, bringing both families together in celebration. Traditional pre-wedding rituals such as Haldi, Pellikuthuru, Mehendi, and other customs followed on December 21st. Sindhu's wedding celebrations followed shortly after her victory at the Syed Modi International tournament in Lucknow earlier that month. This win marked the end of a period without a title for the badminton star. Sindhu is considered one of India's most accomplished athletes. Her achievements include five medals at the BWF World Championships, one of which is a gold, in addition to her two Olympic medals.

Niagara earns 88-69 win against Le Moyne

Revlon Signs Lease to Relocate its New Jersey-based Science and Innovation Lab to The Northeast Science & Technology (NEST) Center

Bethlehem marks a second subdued Christmas during the war in Gaza BETHLEHEM, West Bank (AP) — Bethlehem is marking another somber Christmas Eve under the shadow of war in Gaza. Manger Square lacked its usual festive lights and crowds of tourists on Tuesday. Instead, the area outside the Nativity Church was quiet. The church was built atop the spot where Jesus is believed to have been born. The war, the violence in the occupied West Bank it has spurred and the lack of festivities has deeply hurt Bethlehem's economy. The town relies heavily on Christmas tourism. The economy in the West Bank was already reeling because of restrictions placed on laborers preventing them from entering Israel during the war. Middle East latest: Bethlehem marks a somber Christmas Eve amid war in Gaza TEL AVIV, Israel (AP) — The Palestinian city of Bethlehem is preparing for another somber Christmas under the shadow of war in Gaza. Most festivities cancelled and crowds of tourists absent in the Israeli-occupied West Bank. Winter is hitting the Gaza Strip and many of the nearly 2 million Palestinians displaced by the devastating 15-month war with Israel are struggling to protect themselves from the wind, cold and rain. According to Gaza’s Health Ministry, Israel’s bombardment and ground invasion has killed over 45,000 Palestinians, more than half of them women and children. The Health Ministry does not distinguish between fighters and civilians in its count. Heavy travel day off to a rough start after American Airlines briefly grounds all flights WASHINGTON (AP) — American Airlines briefly grounded flights nationwide due to a technical issue just as the Christmas travel season kicks into overdrive and winter weather is threatening more potential problems for those planning to fly or drive. American flights were cleared to fly by federal regulators about one hour after a national ground stop order was issued by federal regulators Tuesday. The American groundings couldn’t come at a worse time for the millions of travelers expected to fly over the next 10 days. The Transportation Security Administration expects to screen 40 million passengers over the holidays and through January 2. Major storm pounds California's central coast, blamed for man's death and partially collapsing pier SANTA CRUZ, Calif. (AP) — A major storm has pounded California’s central coast bringing flooding and high surf that was blamed for fatally trapping a man beneath debris on a beach and later partially collapsing a pier, tossing three people into the Pacific Ocean. The storm was expected to bring hurricane-force winds and waves up to 60 feet Monday as it gained strength from California to the Pacific Northwest. Some California cities have ordered beachfront homes and hotels to evacuate early Monday afternoon. Forecasters have warned that storm swells would continue to increase throughout the day. Caitlin Clark honored as AP Female Athlete of the Year following her impact on women's sports Caitlin Clark has been named the AP Female Athlete of the Year after raising the profile of women’s basketball to unprecedented levels in both college and the WNBA. She led Iowa to the national championship game, was the top pick in the WNBA draft and captured rookie of the year honors in the league. Fans packed sold-out arenas and millions of television viewers followed her journey on and off the court. Clark's exploits also put other women's sports leagues in the spotlight. A group of 74 sports journalists from AP and its members voted on the award. Other athletes who received votes included Olympic gold medalist Simone Biles and boxer Imane Khelif. Clark’s only the fourth women’s basketball player to win the award since it was first given in 1931. 20 years after the Indian Ocean tsunami, a boy found in the mud embraces being known as 'Baby 81' KURUKKAL MADAM, Sri Lanka (AP) — The boy once known as “Baby 81,” who was pulled from the mud as an infant after the devastating Indian Ocean tsunami in 2004 and reunited with his parents following an emotional court battle, is now a 20-year-old dreaming of higher education. Jayarasa Abilash’s story symbolizes that of the many families torn apart by one of the worst natural calamities in modern history, but it also offers hope. He grew up being followed by the nickname “Baby 81” and feeling embarrassed until he learned more about the events that tore him from his family and brought him back. He has lost his fear. A blast at a Turkish ammunition factory kills 11 people ISTANBUL (AP) — An explosion at an ammunition factory in northwest Turkey left 11 dead and five injured Tuesday morning. The state-run Anadolu Agency says the blast occurred in Balikesir province, in a rural area away from population centers. The provincial governor says one building collapsed and others were damaged, The governor says the explosion was due to a technical issue and there was no possibility of sabotage. An investigation has begun. France has a new government, again. Politics and crushing debt complicate next steps PARIS (AP) — France’s president and prime minister have managed to form a new government just in time for the holidays. Now comes the hard part. Crushing debt, pressure from the nationalist far right, wars in Europe and the Mideast. The hallenges abound for President Emmanuel Macron and Prime Minister Francois Bayrou. They already had a tumultuous 2024. The most urgent order of business is passing a 2025 budget. Financial markets, ratings agencies and the European Commission are pushing France to bring down its deficit. It is threatening the stability and prosperity of all countries that share the euro currency. Inside the Gaetz ethics report, a trove of new details alleging payments for sex and drug use WASHINGTON (AP) — The House Ethics Committee’s long-awaited report into Rep. Matt Gaetz documents a trove of salacious allegations of misconduct, including sex with an underage girl, that tanked the Florida Republican’s nomination to lead the Justice Department. Citing text messages, travel receipts, online payments and other evidence, the committee painted a picture of a lifestyle in which Gaetz and others connected with younger women for drug-fueled parties, events or trips, with the expectation the women would be paid for their participation. Gaetz, who had filed a last-minute lawsuit to try to block the report’s release Monday, slammed the committee’s findings. Gaetz has denied any wrongdoing and has insisted he never had sex with a minor. Legendary Indian filmmaker Shyam Benegal dies at age 90 NEW DELHI (AP) — Shyam Benegal, a renowned Indian filmmaker known for pioneering a cinema movement that tackled social issues in the 1970s, has died after chronic kidney disease. He was 90. His contribution to cinema was recognized as a director, editor and screenwriter. He came into the limelight with films that challenged mainstream Bollywood by dealing with the social realities of a poor nation. He also was a mentor to top Indian actors. India's prime minister says he is “deeply saddened” by Benegal's death.

Cats donors accused of $14.5m fraud against NDIS provider have assets frozenNEW YORK , Dec. 10, 2024 /PRNewswire/ -- Report on how AI is redefining market landscape - The global functional food ingredients market size is estimated to grow by USD 53.14 billion from 2024 to 2028, according to Technavio. The market is estimated to grow at a CAGR of almost 7.38% during the forecast period. The report provides a comprehensive forecast of key segments below- Segmentation Overview 1.1 Probiotics and prebiotics 1.2 Proteins and amino acid 1.3 Dietary fibers 1.4 Vitamins and minerals 1.5 Others 2.1 Food and beverages 2.2 Pharmaceuticals 2.3 Others 3.1 APAC 3.2 North America 3.3 Europe 3.4 Middle East and Africa 3.5 South America Get a glance at the market contribution of rest of the segments - Download a FREE Sample Report in minutes! 1.1 Fastest growing segment: The probiotics and prebiotics segment is the largest product category in the global functional food ingredients market in 2023. Probiotics, such as Lactobacillus, Bifidobacterium, and Enterococcus, are live microorganisms found in fermented dairy products like yogurt, buttermilk, and Greek yogurt. Prebiotics are non-digestible fibers that nourish probiotic bacteria and promote their growth. The increasing consumer awareness about health benefits of probiotics is driving market growth. For instance, Wildwonder, a new prebiotic + probiotic beverage, was launched in June 2023 . This light-carbonated drink, available at Sprouts and online, has five grams of prebiotic fiber, one billion live probiotic organisms, and only six grams of sugar. Probiotics also reduce the risk of diarrhea and colon cancer, while prebiotics offer benefits like calcium and magnesium absorption and improved food quality. Both have significant advantages, making the probiotics and prebiotics segment a key growth area in the functional food ingredients market. Analyst Review The Functional Food Ingredients Market encompasses various processing technologies like High-hydrostatic pressure, Ultrasound-assisted extraction, Microwave-assisted extraction, Pulsed electric field, and Radio-frequency drying, which are used to extract and preserve nutrients and functional compounds from natural sources. These ingredients include Carotenoids such as Beta-carotene, Lutein, and Zeaxanthin, as well as Flavonoids like Quercetin, Kaempferol, Catechins, and Anthocyanidins. Fortified foods have gained popularity due to the rising incidence of Chronic diseases and Micronutrient deficiencies. Technological conditions and Legislative regulations play a significant role in market growth. Supercritical fluids and Probiotic strains are other key components of this market. Middle class consumers and Government fortification programs are major drivers. Minerals, Fiber, Vitamins, and Conjugated linolenic acid are other essential functional food ingredients. International food regulations ensure safety and quality standards are met. Market Overview The Functional Food Ingredients Market encompasses various bioactive components such as Prebiotics and Probiotics, Carotenoids, Vitamins, Minerals, Fiber, and Flavonoids, among others. These ingredients cater to the growing demand for food and beverages that offer health benefits beyond basic nutrition. Chronic diseases like cardiovascular disease, obesity, Alzheimer's disease, and diabetes are driving market growth. Technological advancements in extraction methods, including high-hydrostatic pressure, ultrasound-assisted extraction, microwave-assisted extraction, pulsed electric field, radio-frequency drying, and supercritical fluids, are enhancing the production of functional food ingredients. Nutrigenomics and legislative regulations are key factors influencing market trends. Probiotic strains, antioxidants, anti-inflammatory, and fiber are popular functional ingredients. The market includes various applications such as fortified food, beverages, dietary supplements, animal feed, and pharmaceuticals. Health-conscious consumers, clean labels, and personalization are key market drivers. Functional food ingredients are used in various food categories, including energy drinks, sports drinks, yogurt, kefir, sauces, soups, gravies, frozen desserts, baked goods, and low-fat or calorie-reduced products. Functional food ingredients are also used as texturizing, binding, and thickening agents. The market is expected to grow due to the increasing prevalence of chronic diseases, micronutrient deficiencies, and the middle class's growing demand for healthier food options. Government fortification programs and international food regulations are also impacting market growth. Probiotic ingredients, plant-based proteins, and microorganisms are emerging trends in the market. The market is also influenced by the increasing popularity of e-commerce platforms and the growing demand for organic food and plant-based products. Functional food ingredients offer various health benefits, including cancer risk reduction, cognitive function improvement, and immune system support. Omega-3 supplements and vitamin D supplements are popular functional ingredients in the pharmaceutical segment. The market is expected to grow due to the increasing focus on personalization and precision medicine, as well as the genetic makeup and lifestyle factors. The animal feed industry is also a significant market for functional food ingredients due to the growing demand for animal health and productivity. To understand more about this market- Download a FREE Sample Report in minutes! Key Topics Covered: 1 Executive Summary 2 Market Landscape 3 Market Sizing 4 Historic Market Size 5 Five Forces Analysis 6 Market Segmentation 7 Customer Landscape 8 Geographic Landscape 9 Drivers, Challenges, and Trends 10 Venodr Landscape 11 Vendor Analysis 11.1 Cargill 11.2 Incorporated (US) 11.3 BASF SE ( Germany ) 11.4 ADM (US) 11.5 International Flavors & Fragrances Inc. (US) 11.6 Arla Foods amba ( Denmark ) 11.7 Kerry Group plc ( Ireland ) 11.8 Ajinomoto Co., Inc. ( Japan ) 11.9 DSM ( Netherlands ) 11.10 Ingredion (US) 11.11 Tate & Lyle (UK) 12 Appendix About Technavio Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios. Contacts Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [email protected] Website: www.technavio.com/ SOURCE Technaviofermate From when I first started writing about Lemonade ( NYSE: LMND ) on December 10, 2020, to my last article on the company on May 7, 2024, the question of whether the company would survive existed. However, after listening to the company's Analyst’s Disclosure: I/we have a beneficial long position in the shares of LMND either through stock ownership, options, or other derivatives. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article. Seeking Alpha's Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

Patriots' 2025 opponents set after Week 17 gamesEducation notebook: Boundary adjustments, pitch nights and board meetingsSmokers have been urged to kick the habit in the new year after new analysis shows how much of their lives are lost by each cigarette smoked. Men lose 17 minutes of life with every cigarette they smoke while a woman’s life is cut short by 22 minutes with each cigarette, experts have estimated. This is more than previous estimates, which suggest that each cigarette shortens a smoker’s life by 11 minutes. The new estimates, which suggest that each cigarette leads to 20 minutes loss of live on average across both genders, are based on more up-to-date figures from long-term studies tracking the health of the population. Researchers from University College London said that the harm caused by smoking is “cumulative” and the sooner a person stops smoking, and the more cigarettes they avoid smoking, the longer they live. The new analysis, commissioned by the Department for Health and Social Care, suggests that if a 10-cigarettes-a-day smoker quits on January 1, then by January 8 they could “prevent loss of a full day of life”. By February 20, their lives could be extended by a whole week. And if their quitting is successful until August 5, they will likely live for a whole month longer than if they had continued to smoke. The authors added: “Studies suggest that smokers typically lose about the same number of healthy years as they do total years of life. Make 2025 the year you quit smoking for good. There’s lots of free support available to help you. Find out more 🔽 https://t.co/J0ehnoRM1D pic.twitter.com/LQpUp6HJBm — WHH 🏥 (@WHHNHS) December 27, 2024 “Thus smoking primarily eats into the relatively healthy middle years rather than shortening the period at the end of life, which is often marked by chronic illness or disability. “So a 60-year-old smoker will typically have the health profile of a 70-year-old non-smoker.” The analysis, to be published in the Journal of Addiction, concludes: “We estimate that on average, smokers in Britain who do not quit lose approximately 20 minutes of life expectancy for each cigarette they smoke. “This is time that would likely be spent in relatively good health. “Stopping smoking at every age is beneficial but the sooner smokers get off this escalator of death the longer and healthier they can expect their lives to be.” Dr Sarah Jackson, principal research fellow from the UCL Alcohol and Tobacco Research Group, said: “It is vital that people understand just how harmful smoking is and how much quitting can improve their health and life expectancy. “The evidence suggests people lose, on average, around 20 minutes of life for each cigarette they smoke. “The sooner a person stops smoking, the longer they live. “Quitting at any age substantially improves health and the benefits start almost immediately. “It’s never too late to make a positive change for your health and there are a range of effective products and treatments that can help smokers quit for good.” There are so many reasons to quit smoking this New Year – for your health, for more money, and for your family. Make a fresh quit for 2025 – find tips and support at https://t.co/GyLk65o8kS or https://t.co/iW6WLxTL00 pic.twitter.com/KxPZ5N378y — North Tees and Hartlepool NHS Foundation Trust (@NTeesHpoolNHSFT) December 27, 2024 Health officials have said that smokers can find advice, support and resources with the NHS Quit Smoking app, as well as the online Personal Quit Plan. Public health minister Andrew Gwynne said: “Smoking is an expensive and deadly habit and these findings reveal the shocking reality of this addiction, highlighting how important it is to quit. “The new year offers a perfect chance for smokers to make a new resolution and take that step.” Commenting on the paper, Professor Sanjay Agrawal, special adviser on tobacco at the Royal College of Physicians, said: “Every cigarette smoked costs precious minutes of life, and the cumulative impact is devastating, not only for individuals but also for our healthcare system and economy. “This research is a powerful reminder of the urgent need to address cigarette smoking as the leading preventable cause of death and disease in the UK.”

Ross Barkley’s 85th-minute winner gave them victory after they had twice squandered the lead in Germany. John McGinn and Jhon Duran goals at the start of each half were cancelled out by Lois Openda and Christoph Baumgartner. But Barkley had the final say less than two minutes after coming off the bench as his deflected effort earned the points which sent his side third in the new Champions League league phase. The top eight automatically qualify for the next stage and with games against Monaco and Celtic to come, Unai Emery’s men are a good bet to avoid the need for a play-off round in their first foray in this competition. Leipzig are out, having lost all six of their games. Villa enjoyed a dream start and were ahead with less than three minutes on the clock. Matty Cash, playing in a more advanced position on the right, crossed for Ollie Watkins, who nodded down into the path of McGinn and the skipper made no mistake from close range. That gave the visitors confidence and they had enough chances in the first 15 minutes to have the game wrapped up. Lucas Digne’s cross from the left was begging to be converted but Watkins could not make contact from close range and then Morgan Rogers shot straight at Leipzig goalkeeper Peter Gulacsi. Then Youri Tielemans found himself with time and space on the edge of the area from Watkins’ tee-up but the Belgium international disappointingly dragged wide. All that good work was undone in the 27th minute, though, as Emiliano Martinez was left red-faced. The Argentinian was too casual waiting to collect Nicolas Seiwald’s long ball and Openda nipped in to get the ball first and tap into an empty net. Duran was introduced at the break and needed just a couple of minutes to fire a warning when he drilled wide after a loose ball fell to him 14 yards out. But the Colombian got his goal in the 52nd minute, though it was another moment for the goalkeeper to forget. Duran was invited to drive forward and unleashed a 25-yard shot, which was hardly an Exocet, but still was too much for Gulacsi, who barely even jumped. It was his 10th goal of the season and sixth from the bench as he continues his super-sub role. The striker was not complaining and he thought he had doubled his tally shortly after when he converted Cash’s centre but the provider was ruled offside by VAR. Five minutes later, Villa found themselves pegged back again with a finish of real quality. Openda was sent clear by another long ball and his cross was perfect for Baumgartner to cushion a far-post volley back across goal and into the corner. Digne brought a save out of Gulacsi and then Openda shot straight at Martinez as both sides pushed for a winner. It was Villa who got it as Barkley saw his deflected effort wrong-foot Gulacsi and hit the back of the net.