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BX-004 is under clinical development by BiomX and currently in Phase II for Cystic Fibrosis. According to GlobalData, Phase II drugs for Cystic Fibrosis have a 31% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. BX-004 overview BX-004 is under development for the treatment of cystic fibrosis, non-cystic fibrosis bronchiectasis and resistant pseudomonas aeruginosa infections. It is administered as inhalational formulation. The drug candidate comprises of cocktail of natural phages developed based on BOLT (Bacteriophage Lead to Treatment) platform. BiomX overview BiomX is a microbiome company that develops natural and engineered phage cocktails targeting harmful bacteria in chronic diseases and conditions such as cystic fibrosis and diabetic foot osteomyelitis. The company’s pipeline products include BX004 to treat cystic fibrosis (CF) and BX211 for the treatment of diabetic foot osteomyelitis (DFO). It utilizes its proprietary BOLT platform to develop phage-based product candidates. It works in collaboration with Janssen Pharmaceuticals, , and Co. Ltd. BiomX is headquartered in Ness Ziona, Israel. For a complete picture of BX-004’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .
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