Trump selects longtime adviser Keith Kellogg as special envoy for Ukraine and RussiaHENDERSON, Nev. (AP) — Aidan O'Connell will start at quarterback when the Las Vegas Raiders visit their AFC West rival and two-time defending Super Bowl champion Kansas City Chiefs on Friday. Raiders coach Antonio Pierce made the announcement Wednesday, saying O'Connell had progressed well after breaking his right thumb on Oct. 20 in a 20-15 loss to the Los Angeles Rams . “He’s been dialed in obviously throughout this time that he’s been on (injured reserve),” Pierce said. "He’s been at all the meetings. He’s been very encouraging on the sideline. He’s got that laser-eye focus right now. Great opportunity for him.” Gardner Minshew broke his left collarbone on Sunday in a game against the Denver Broncos and is out for the season . The Raiders could have gone with Desmond Ridder to replace Minshew. Las Vegas signed Ridder off Arizona’s practice squad on Oct. 21. He started 13 games for Atlanta last season, passing for 2,836 yards and 12 touchdowns with 12 interceptions. Pierce opted for O'Connell, who became the starter midway through last season and went 5-4 the rest of the way. Minshew beat him out for the job in the preseason but then struggled through five games. Pierce then put O'Connell in the starting lineup on Oct. 13 against the Pittsburgh Steelers. O'Connell completed 27 of 40 passes for 227 yards and a touchdown with an interception in the 32-13 loss . Then O'Connell was injured early the following week at Los Angeles and was placed on IR, sidelining him for at least four weeks. The Raiders on Monday designated him to return to practice, opening a three-week window in which O'Connell could be activated. That came this week. “He carried himself like a starter, even when he was on IR," Pierce said. "He did that when he was a backup. He did a great job of just being engaged with the players, engaged on the sideline, in meeting rooms. He’s the one speaking up, talking. You could just look at his eyes. You can look at his demeanor. "He wasn’t a guy like: ‘All right, I’m out for the season. I’m not going to play. No, I’ll be back. I’m ready to be back.’ And he worked his tail off to get back.” O'Connell has a short week to prepare, complicated further because the Raiders aren't having full practices. He was the last opposing quarterback to win at Arrowhead Stadium. Even though he didn't complete a pass after the first quarter, the Raiders walked away 20-14 winners in that Christmas Day game. Las Vegas can only play a little bit of a spoiler this week. The Raiders at 2-9 have lost seven consecutive games, and the Chiefs have their sights on becoming the first team to win three Super Bowls in a row. “Let’s call a spade a spade,” Pierce said. "The best team in football against the worst team in football. Let’s change the narrative, right? Let’s go out there and make it a dog fight. Let’s make it ugly. Let’s make it scrappy. It’s Black Friday. Let’s create a little chaos. Let’s get back to Raider football and have some fun and some personality. Let it loose.” AP NFL: https://apnews.com/hub/NFL
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The hunt for UnitedHealthcare CEO's elusive killer yields new evidence, but few answersAfter further review, DeShaun Foster has reversed his stance on one central figure in the halftime brouhaha during the crosstown rivalry game. The UCLA coach acknowledged Wednesday that head performance coach Corey Miller — whom Foster had initially labeled a peacemaker — escalated tensions between the teams last weekend after video surfaced showing Miller making a mock crying gesture and giving USC players the middle finger. Miller expressed regret for his actions, Foster said, and would face unspecified discipline. “We talked about it, sat down and was able to figure that out internally and he felt pretty bad about that,” Foster said, “so he expressed his sentiments to the team, to the coaches and everybody and you’ve got to lead by example out here. You can’t be completely — you just can’t be out of control in any situation, especially when you’re in a [position] of power, so it was an unfortunate situation and he feels awful about what happened and getting a penalty and he made sure he made it right with the team.” Miller received one of three unsportsmanlike conduct penalties that went against UCLA, joining wide receiver Kwazi Gilmer and safety Bryan Addison. Foster said after the game that he was told the fracas started when a USC player punched Gilmer. UCLA was forced to kick off from its own five-yard line to start the third quarter as a result of the penalties, but the Trojans could not gain a first down and gave the ball back to the Bruins following a turnover on downs. Foster brought Miller back to UCLA to be part of his new staff before the season after Miller had spent the 2022 season as the Bruins’ director of speed and movement. Miller was the assistant director of strength and conditioning for the NFL’s Carolina Panthers during the 2023 season. “With his added NFL experience,” Foster said at the time of Miller’s hiring, “I feel there is no one better to uphold our pillars while preparing the Bruins for Big Ten Conference play and beyond.” Mo’ Money? Foster said he nominated defensive coordinator Ikaika Malloe for the Broyles Award that goes to the top assistant coach in college football. Might Foster also need to give Malloe a raise given that UCLA lost its last defensive coordinator when D’Anton Lynn doubled his salary by moving across town to USC? “This is a real family over here, so I think that he’s pretty comfortable,” Foster said, “but we still want to make sure that we honor him and let him know that we do value you and you’re a great coach for us.” Malloe’s two-year contract that expires after the 2025 season pays him $1 million annually — the same rate that Lynn made before his departure. Despite massive personnel losses in the offseason, Malloe has presided over a defense that ranks No. 7 in the country against the run by allowing just 99.3 rushing yards per game. UCLA ranks No. 46 nationally in total defense, giving up 346.3 yards per game. Decisions, decisions UCLA’s defense could get a major boost next season if Carson Schwesinger stays put. The linebacker who has gone from a walk-on to a finalist for the Butkus Award has another season of eligibility remaining, should he choose to use it. “He’s let me know early like, coach, we’re just going to finish the season and then assess everything after the season,” Foster said of Schwesinger’s message regarding his future. “He’s truly locked in on finishing this year the right way and I can respect that from a guy like that. I didn’t want to even want to put anything in his ear because whatever decisions he makes, I’m going to respect that because Carson’s that type of kid. He’s really going to do whatever’s best for him in that situation, especially if he gets the Butkus Award and the way that he came on and performed this season, you do deserve to get a shot and go to the NFL.” With the transfer portal set to open Dec. 9, Foster said, with a chuckle, that he wanted to know his players’ intentions about their futures by Dec. 5. “There’s a hard turnaround,” Foster said, “so we just want to make sure that we know exactly what’s going on with our team and how guys are feeling, so we know what we need to fill and what we need to do.”
Should assisted dying be legalised in U.K.? | Explained-- Shares Facebook Twitter Reddit Email This article was originally published on The Conversation . Medical accounts of red wine headaches go back to Roman times , but the experience is likely as old as winemaking – something like 10,000 years . As chemists specializing in winemaking , we wanted to try to figure out the source of these headaches. Many components of red wine have been accused of causing this misery – sulfites , biogenic amines and tannin are the most popular. Our research suggests the most likely culprit is one you may not have considered. The common suspects Sulfites have been a popular scapegoat for all sorts of ailments since it became mandatory in the 1990s to label them on wines in the U.S. However, not much evidence links sulfites directly to headaches, and other foods contain comparable levels to wine without the same effects. White wines also contain the same amount of sulfites as red wines . Your body also produces about 700 milligrams of sulfites daily as you metabolize the protein in your food and excrete it as sulfate . To do so, it has compounds called sulfite oxidases that create sulfate from sulfite – the 20 milligrams in a glass of wine are unlikely to overwhelm your sulfite oxidases. Some people point the finger for red wine headaches at biogenic amines. These are nitrogenous substances found in many fermented or spoiled foods, and can cause headaches, but the amount in wine is far too low to be a problem. Tannin is a good guess , since white wines contain only tiny amounts, while red wines contain substantial amounts. Tannin is a type of phenolic compound – it's found in all plants and usually plays a role in preventing disease, resisting predation or encouraging seed dispersal by animals. But there are many other phenolic compounds in grapes' skin and seeds besides tannin that make it into red wines from the winemaking process, and are not present in white, so any of them could be a candidate culprit. Tannin is also found in many other common products, such as tea and chocolate, which generally don't cause headaches. And phenolics are good antioxidants – they're unlikely to trigger the inflammation that would cause a headache. A red wine flush Some people get red, flushed skin when drinking alcohol, and the flushing is accompanied by a headache . This headache is caused by a lagging metabolic step as the body breaks down the booze. The metabolism of alcohol happens in two steps. First, ethanol is converted to acetaldehyde. Then, the enzyme ALDH converts the acetaldehyde to acetate, a common and innocuous substance. This second step is slower for people who get flushed skin, since their ALDH is not very efficient. They accumulate acetaldehyde , which is a somewhat toxic compound also linked to hangovers . Leftover acetaldehyde not converted into acetate can cause hangover symptoms. Compound Chemistry , CC BY-NC-ND So, if something unique in red wine could inhibit ALDH, slowing down that second metabolic step, would that lead to higher levels of acetaldehyde and a headache? To try to answer this question, we scanned the list of phenolics abundant in red wine. We spied a paper showing that quercetin is a good inhibitor of ALDH. Quercetin is a phenolic compound found in the skins of grapes, so it's much more abundant in red than white wines because red grape skins are left in longer during the fermentation process than white grape skins. Putting enzymes to the test Testing ALDH was the next step. We set up an inhibition assay in test tubes. In the assay, we measured how fast the enzyme ALDH breaks down acetaldehyde. Then, we added the suspected inhibitors – quercetin, as well as some other phenolics we wanted to test – to see whether they slowed the process. The chemical structure of quercetin, which may cause red wine headaches. Johannes Botne , CC BY-SA These tests confirmed that quercetin was a good inhibitor. Some other phenolics had varying effects, but quercetin glucuronide was the winner. When your body absorbs quercetin from food or wine, most is converted to glucuronide by the liver in order to quickly eliminate it from the body. Our enzyme tests suggest that quercetin glucuronide disrupts your body's metabolism of alcohol. This disruption means extra acetaldehyde circulates, causing inflammation and headaches. This discovery points to what's known as a secondary, or synergistic, effect . These secondary effects are much harder to identify because two factors must both be in play for the outcome to arise. In this case, other foods that contain quercetin are not associated with headaches, so you might not initially consider quercetin as the cause of the red wine problem. The next step could be to give human subjects two red wines that are low and high in quercetin and ask whether either wine causes a headache. If the high-quercetin wine induces more headaches, we'd know we're on the right track. So, if quercetin causes headaches, are there red wines without it? Unfortunately, the data available on specific wines is far too limited to provide any helpful advice. However, grapes exposed to the Sun do produce more quercetin, and many inexpensive red wines are made from grapes that see less sunlight. If you're willing to take a chance, look for an inexpensive, lighter red wine. Andrew Waterhouse , Professor of Enology, University of California, Davis and Apramita Devi , Postdoctoral researcher in food science and technology, University of California, Davis This article is republished from The Conversation under a Creative Commons license. Read the original article . By Andrew Waterhouse MORE FROM Andrew Waterhouse By Apramita Devi MORE FROM Apramita Devi Related Topics ------------------------------------------ Food Grapes Headache Health Partner Red Wine The Conversation Wine Related Articles Advertisement:Trump selects longtime adviser Keith Kellogg as special envoy for Ukraine and Russia
Retiring Naeher is proud of her achievements and looking forward to USWNT's next generationSherwin-Williams SVP sells $2.05 million in stock at $398.06 per shareBay State pols call on Postal Service to fix delivery issues ahead of the holidaysNew Delhi: Reeling under election losses, the Congress party will devote 2025 for a major organisational revamp that will see more young leaders in key posts, examination of “capabilities of leaders” and fulfilment of the key tasks set at the party’s Udaipur Chintan Shivir in 2022. In his inaugural speech at the Congress Working Committee meeting at Belagavi on Thursday, Congress president Mallikarjun Kharge said that 2025 will be “the year of our organisation’s empowerment.” “We will fill all the vacant posts in the organisation. We will fully implement the Udaipur Declaration. We will equip our organisation with the necessary skills to win elections from AICC to Mandal and booth. We will have to find such people who are ideologically committed, who are ready to fight to protect the Constitution, who believe in the Congress Party’s Idea of India. Such people have to be connected to the party and brought into the mainstream,” he said. Of the seven tasks set at the Udaipur conclave, the Congress has implemented four suggestions including the expansion of the CWC to include 50% youth, women, SC, ST and OBC members. However, one person one post, restriction of tickets to families and the setting up of an election management cell remain pending. “Only hard work is not enough, time-bound solid strategy and direction is necessary. There is a need to give a chance to new power and bring up local and new leadership. We have the power of ideas, the legacy of Gandhi-Nehru and the heritage of great heroes. We will return from Belgaum with a new message and new resolution,” Kharge added. A section of the Congress feels that the party will push for more young leaders in crucial roles and put a premium on ideological commitment. “The emphasis on fulfilling the Udaipur declaration is important as many key tasks, including creating a dedicated election management cell, is pending,” said a Congress leader, asking not to be named. “There are major decisions. More than 50 leaders participated in the discussions. Kharge and Rahul Gandhi both spoke in depth. We have decided that 2025 is going to see organisation revamp programme at every level, booth to top examination of capability,” said KC Venugopal. In its resolution on Gandhi, the Congress said, “The Congress Working Committee reaffirms its unwavering commitment to the values that defined Mahatma Gandhi’s entire life, to the causes he championed relentlessly and the ideals he upheld. It recalls that Mahatma Gandhi’s life was anchored in truth, non-violence, fearlessness and simplicity.” “It was dedicated to the gaining of political freedom along with profound societal transformation. India has achieved a great deal since independence. But even as our country has progressed impressively, his relevance has only become more significant. In our continued quest for deeper social and economic justice and growth with ecological balance he continues to be a guide and a moral compass. In our continued pursuit of communal harmony and amity, without which economic advancement will have little meaning, he remains the exemplar.”
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Daily Post Nigeria Police arrest man, 40, for raping minor in Edo Home News Politics Metro Entertainment Sport Metro Police arrest man, 40, for raping minor in Edo Published on November 27, 2024 By Enahoro Iyemefokhai Operatives of the Edo State Police Command have arrested 40-year-old Monday Obakpian for allegedly raping a 14-year-old girl. DAILY POST reports that the Public Relations Officer of the command, SP Moses Yamu, disclosed this on Wednesday in a statement made available to newsmen in Benin City. Yamu said the suspect, who resides at Odo Quarters in Ibillo, Akoko Edo Local Government Area of the state, lured the innocent girl into his room under the guise of sending her on an errand. The police spokesman said the suspect took advantage of the situation and forcefully had carnal knowledge of her. Yamu explained that a neighbour who heard the victim screaming from the suspect’s room notified the police He said the suspect who confessed to the crime would soon be charged in court. The command called on members of the public to contribute to preventing or stopping violence, especially against women and girls. “This also serves as a warning to the general public, particularly perpetrators of these heinous crimes, that the command will do everything in its power to protect the vulnerable and bring the criminals of such dastardly acts to book,” Yamu said. Related Topics: edo police Don't Miss Police arrest 25 year old man for sodomizing 12 children in Jigawa You may like Gov Okpebholo suspends free bus services earlier approved for Edo residents Police arrest 25 year old man for sodomizing 12 children in Jigawa Police rescue two female kidnap victims in Anambra, arrest four suspects Imo Police vow to enforce law prohibiting gender-based violence against women, children Alleged Rape: Dismissed Inspector Uduma connived with husband to blackmail Sgt Uzuobo – Police Police arrest suspects, recover arms, counterfeit currency, drugs in FCT Advertise About Us Contact Us Privacy-Policy Terms Copyright © Daily Post Media LtdMum and son were doing what they loved before tragedy struck
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