Arizona WR Tetairoa McMillan to enter 2025 NFL DraftLiverpool's Premier League lead cut as Newcastle gain drawkijiji halifax jobs 。

Trump names Andrew Ferguson as head of Federal Trade Commission to replace Lina Khan5 Offline Apps Every Traveler Needs For Stress-Free JourneysItuka scores 18 off the bench, Jacksonville State downs East Carolina 86-78

Donald Trump is returning to the world stage. So is his trolling

DETROIT (AP) — General Motors said Tuesday it will retreat from the robotaxi business and stop funding its money-losing Cruise autonomous vehicle unit. Instead the Detroit automaker will focus on development of partially automated driver-assist systems for personal vehicles like its Super Cruise, which allows drivers to take their hands off the steering wheel. GM said it would get out of robotaxis “given the considerable time and resources that would be needed to scale the business, along with an increasingly competitive robotaxi market.” The company said it will combine Cruise's technical team with its own to work on advanced systems to assist drivers. GM bought control of San Francisco-based Cruise automation in 2016 with high hopes of developing a profitable fleet of robotaxis. Over the years GM invested billions in the subsidiary and eventually bought 90% of the company from investors, all while racking up millions in losses. GM’s brushoff of Cruise represents a dramatic about-face from years of full-blown support that left a huge financial dent in the automaker. The company invested $2.4 billion in Cruise only to sustain years of uninterrupted losses, with little in return. Since GM bought a controlling stake in Cruise for $581 million in 2016, the robotaxi service piled up more than $10 billion in operating losses while bringing in less than $500 million in revenue, according to GM shareholder reports filed with the Securities and Exchange Commission. The automaker even announced plans for Cruise to generate $1 billion in annual revenue by 2025, but it scaled back spending on the company after one of its autonomous Chevrolet Bolts dragged a San Francisco pedestrian who was hit by another vehicle in 2023. The California Public Utilities Commission alleged Cruise then covered up details of the crash for more than two weeks. The embarrassing incident resulted in Cruise’s license to operate its driverless fleet in California being suspended by regulators and triggered a purge of its leadership — in addition to layoffs that jettisoned about a quarter of its workforce . GM CEO Mary Barra told analysts on a conference call Tuesday the the new unit will focus on personal vehicles and developing systems that can drive by themselves in certain circumstances. The company has agreements to buy another 7% of Cruise and intends to buy the remaining shares so it owns the whole company. The move is another step back from autonomous vehicles, which have proved far harder to develop than companies once anticipated. Two years ago, crosstown rival Ford Motor Co. disbanded its Argo AI autonomous vehicle venture in Pittsburgh that it co-owned with Volkswagen. At the time the company said it didn’t see a path to profitability for a number of years. Yet other companies are pressing forward with plans to deploy autonomous vehicles and expanding their services. Alphabet Inc.'s Waymo is accelerating plans to broaden its robotaxi service beyond areas of metropolitan Phoenix, San Francisco and Los Angeles. Last week the company said it would begin testing its driverless Jaguars in Miami next year, with plans to start charging for rides in 2026. The move comes less than a month after Waymo opened up its robotaxi service to anyone looking for a ride in an 80-square-mile (129 square kilometer) area of Los Angeles. Waymo also has plans to launch fleets in Atlanta and Austin next year in partership with ride-hailing leader Uber. In April, a company called Aurora Innovation plans to start hauling freight on Texas freeways using fully driverless semis. Tesla CEO Elon Musk has said his company plans to have autonomous Models Y and 3 running without human drivers next year. Robotaxis without steering wheels using Tesla's “Full Self-Driving” system would be available in 2026 starting in California and Texas, he said. But an investigation by the National Highway Traffic Safety Administration into Full Self-Driving's ability to see in low visibility conditions cast doubt on whether Teslas are ready to be deployed without humans behind the wheel. The agency began the investigation in October after getting reports of four crashes involving “Full Self-Driving” when Teslas encountered sun glare, fog and airborne dust. An Arizona pedestrian was killed in one of the crashes. GM said it will work with Cruise’s leadership to restructure the company and refocus Cruise’s operations on driver assist systems. The company expects the restructuring to reduce spending by more than $1 billion annually. Cruise has about 2,300 employees and will retain a presence in San Francisco, GM said. It’s too early to talk about employment levels until the restructuring is completed next year, a spokesman said. Dave Richardson, senior vice president of software and services engineering, said Cruise will bring its software, artificial intelligence and sensor development to GM to team up on improving GM’s driver-assist systems. “We want to leverage what already has been done as we go forward, and we think we can do that very effectively,” Barra said. Shares of GM rose about 3% in trading after Tuesday's closing bell. They are up about 47% for the year. AP Technology Writer Michael Liedtke in San Francisco contributed to this report.MINNEAPOLIS, Nov. 22, 2024 (GLOBE NEWSWIRE) -- Atomic Data today announced a multi-year agreement to make it the Official IT Provider of Fishers Event Center , a 7,500-seat entertainment and sporting event venue opening today in Fishers, Indiana. Managed by ASM Global , the newly constructed Fishers Event Center is home to three professional sports teams – Indy Fuel Hockey Club (ECHL), Indy Ignite (Professional Volleyball Federation), and Fishers Freight (Indoor Football League) – and will host a wide variety of events, concerts, and entertainment. “We are thrilled to reach a multi-year deal partnership with Atomic Data,“ Larry McQueary , Indy Fuel president said. “Atomic Data has been an integral part of the building process at the Fishers Event Center. With their help, we are ensuring an elevated experience for fans, employees and the community as they experience events here.” Throughout construction, Atomic Data’s Game Day Technologies ® arm took the lead in the design, installation, integration, and testing of the mid-size venue’s HPE Aruba Networking-powered Local Area Network (LAN) and Wi-Fi network. Going forward as the Official IT Provider for Fishers Event Center, Atomic Data will provide 24x7 monitoring and management of key network and server infrastructure, as well as remote support during and between event days. "Venues like Fishers are essential to cities across the U.S., supporting a variety of events and teams. Their success relies on seamless behind-the-scenes technology. Atomic Data and Game Day Technologies have once again proven that tailored venue technology can be delivered efficiently, even with tight timelines and modest budgets," commented Yagya Mahadevan , Game Day Technologies Director at Atomic Data. About Atomic Data Atomic Data , trusted IT provider for hundreds of enterprises, sports teams, and large venues, is on a mission to deliver always-on, custom-tailored technology solutions and objective IT leadership. Game Day Technologies , powered by Atomic Data, enables owners and teams to right size and modernize their venues, districts, training facilities, and back offices with objective, holistic technology oversight and activation. Media Contact: Atomic Data, Scott Evangelist, marketing@atomicdata.com

None

12. Clemson Tigers 10-3 (7-1 Atlantic Coast Conference regular season) What's next: First-round at No. 5 seed Texas, Dec. 21 Head coach: Dabo Swinney (17th season, 180-46 overall) About Swinney: The 55-year-old, who is 6-4 in the CFP, took over during the 2008 season and has won two national titles (2016, 2018). He will take the Tigers to the CFP the first time since the 2020 season and the seventh time overall. Resume The Tigers, the only three-loss team in the 12-team field, were in a must-win situation in the ACC championship game, prevailing on a last-second, 56-yard field goal to defeat SMU 34-31. Clemson lost two games to SEC opponents (Georgia and South Carolina) this season. The Tigers' other defeat came at home to Louisville. The matchup with Texas will be Clemson's first true road game against the SEC this season. Postseason history A nine-time winner of the ACC Championship Game, the Tigers notched a double-figure win total for the 13th time in the last 14 seasons. Along with its two national titles, Clemson reached the title game two other times (2019 and 2015). This will be the first Clemson-Texas matchup. The road to Atlanta It will be a tricky road for the Tigers to reach the CFP title game in Atlanta at a venue familiar to Clemson fans. The Tigers will take at least two and maybe three trips outside of their own time zone to qualify for the final. Names to know QB Cade Klubnik Klubnik, a Texas native, has been taking snaps in crucial situations since a limited role as a freshman in 2022, when he rescued the Tigers in an ACC Championship victory vs. North Carolina. Sporting a 19-8 career record as a starter, Klubnik has thrown for 3,303 yards and 33 touchdowns along with five interceptions this season. He tossed four TDs in the ACC title game Dec. 7 against SMU after receiving All-ACC honorable mention following the regular season. "He's battle-tested," Swinney said. "He has got a lot of experience under his belt. He has had some failure, which has made him better." RB Phil Mafah The senior has racked up 1,106 rushing yards with eight touchdowns this season and has 28 career scores. Mafah has averaged fewer than 17 carries per game, so he makes the most of his opportunities, and at 230 pounds he can be a load to bring down. DE T.J. Parker He's been disruptive on a regular basis, racking up 19 tackles for loss (11 sacks) this season. The 265-pound sophomore helped set the tone in the ACC title game when the Tigers feasted on early SMU mistakes. Parker is tied for the Division I lead with six forced fumbles this season. K Nolan Hauser The freshman joined the Tigers this season with great acclaim and produced a career highlight with a 56-yard game-winning field goal -- the longest in ACC title game history -- to beat SMU at the buzzer. --Field Level MediaBy CHRISTOPHER RUGABER WASHINGTON (AP) — President-elect Donald Trump on Tuesday named Andrew Ferguson as the next chair of the Federal Trade Commission . He will replace Lina Khan, who became a lightning rod for Wall Street and Silicon Valley by blocking billions of dollars’ worth of corporate acquisitions and suing Amazon and Meta while alleging anticompetitive behavior . Ferguson is already one of the FTC’s five commissioners, which is currently made up of three Democrats and two Republicans. “Andrew has a proven record of standing up to Big Tech censorship, and protecting Freedom of Speech in our Great Country,” Trump wrote on Truth Social, adding, “Andrew will be the most America First, and pro-innovation FTC Chair in our Country’s History.” Related Articles National Politics | Donald Trump is returning to the world stage. So is his trolling National Politics | Biden says he was ‘stupid’ not to put his name on pandemic relief checks like Trump did National Politics | Biden issues veto threat on bill expanding federal judiciary as partisan split emerges National Politics | Trump lawyers and aide hit with 10 additional felony charges in Wisconsin over 2020 fake electors National Politics | After withdrawing as attorney general nominee, Matt Gaetz lands a talk show on OANN television The replacement of Khan likely means that the FTC will operate with a lighter touch when it comes to antitrust enforcement. The new chair is expected to appoint new directors of the FTC’s antitrust and consumer protection divisions. “These changes likely will make the FTC more favorable to business than it has been in recent years, though the extent to which is to be determined,” wrote Anthony DiResta, a consumer protection attorney at Holland & Knight, in a recent analysis . Deals that were blocked by the Biden administration could find new life with Trump in command. For example, the new leadership could be more open to a proposed merger between the country’s two biggest supermarket chains, Kroger and Albertsons, which forged a $24.6 billion deal to combine in 2022. Two judges halted the merger Tuesday night. The FTC had filed a lawsuit in federal court earlier this year to block the merger, claiming the deal would eliminate competition, leading to higher prices and lower wages for workers. The two companies say a merger would help them lower prices and compete against bigger rivals like Walmart. One of the judges said the FTC had shown it was likely to prevail in the administrative hearing. Yet given the widespread public concern over high grocery prices, the Trump administration may not fully abandon the FTC’s efforts to block the deal, some experts have said. And the FTC may continue to scrutinize Big Tech firms for any anticompetitive behavior. Many Republican politicians have accused firms such as Meta of censoring conservative views, and some officials in Trump’s orbit, most notably Vice President-elect JD Vance, have previously expressed support for Khan’s scrutiny of Big Tech firms. In addition to Fergson, Trump also announced Tuesday that he had selected Jacob Helberg as the next undersecretary of state for economic growth, energy and the environment. Click to share on Facebook (Opens in new window) Click to share on X (Opens in new window) Most Popular Colonial Williamsburg’s Grand Illumination has echoes across the US Colonial Williamsburg's Grand Illumination has echoes across the US New York prosecutors charge suspect in UnitedHealthcare CEO killing with murder, court records show New York prosecutors charge suspect in UnitedHealthcare CEO killing with murder, court records show Cause of underground fire at Williamsburg Premium Outlets still unknown — and may stay that way, fire chief says Cause of underground fire at Williamsburg Premium Outlets still unknown — and may stay that way, fire chief says Disney influencer Dominique Brown dies at 34 after allergic reaction at food event, report says Disney influencer Dominique Brown dies at 34 after allergic reaction at food event, report says Former NFL player opens Newport News youth empowerment center Former NFL player opens Newport News youth empowerment center Chesapeake man charged after shooting at Suffolk church staff member Chesapeake man charged after shooting at Suffolk church staff member Inside Business recognizes 2024 Women in Business honorees Inside Business recognizes 2024 Women in Business honorees Well-known Virginia Tech professor Nikki Giovanni remembered as talented poet and literary celebrity Well-known Virginia Tech professor Nikki Giovanni remembered as talented poet and literary celebrity The Dome, Virginia Beach’s upcoming venue, is booking shows. Here’s what’s coming. The Dome, Virginia Beach’s upcoming venue, is booking shows. Here’s what’s coming. David Teel: An exclusive look behind the curtain at ACC headquarters on bowl selection Sunday David Teel: An exclusive look behind the curtain at ACC headquarters on bowl selection Sunday Trending Nationally Who is Luigi Mangione, arrested in connection with shooting of UnitedHealthcare CEO Brian Thompson? California’s home insurance crisis: Which Bay Area neighborhoods have lost the most coverage Tested positive for python? DNA tests will reveal where hard-to-find snakes are Traffic stops by Denver police plunge nearly 50% after new policy prohibits low-level enforcement The stars have come out at the Kennedy Center for Coppola, the Grateful Dead, Raitt and Sandoval

First batch of Canadian-made low-carbon jet fuel emerges from B.C. refinery

Washington Nationals win lottery for No. 1 pick in next amateur baseball draft, Angels No. 2Vici Launches “Proposal To Pitch” to Transform Media Sales PresentationsFilamon Limited, an Australian biotech company focused on developing next-gen anti-inflammatory drugs, has announced its breakthrough dementia treatment. ALPHA-003 is designed to preserve the integrity of vital brain cell structures and protect them against destruction caused by brain inflammation. In healthy neurons, the tau protein stabilizes , crucial tube-like structures that, together with neurofilaments, maintain the neurons’ shape and provide mechanical support. However, when it’s modified, tau can form – tangles that degrade these key structures. This is seen in a group of diseases called tauopathies, such as dementia, including Alzheimer’s disease, and (CTE). Existing dementia treatments focus on reducing the consequences of this structural damage but have enjoyed only moderate success. Now, an Australian biotech company, Filamon Limited, has announced its breakthrough treatment, , which is aimed at halting the progression of dementia by preventing microtubular destruction. “The underlying problem with most forms of dementia is the destruction of a key structural component of brain cells known as microtubules,” said Associate Professor Kieran Scott, Professor of Oncology at Western Sydney University, and co-founder of Filamon. “These long, hollow tubes are vital to healthy brain function. In dementia, these microtubules degrade, resulting in the death of brain cells. “To date, no one has found a way of preventing microtubular destruction,” Scott said. “We believe ALPHA-003 has the potential to be that first drug by stabilizing the two main brain cell components whose job is to protect microtubules from damage – tau and neurofilaments.” ALPHA-003 is designed to prevent damaging brain inflammation by binding to tau and neurofilaments, providing the microtubular protection that Scott is referring to. The result of deep-learning, computational drug design technology developed in Australia, ALPHA-003 started life as a more general anti-inflammatory drug, countering the effects of human group IIA secretory phospholipase A (hGIIA), a significant player in inflammatory conditions, before its developers realized its potential for treating neuroinflammation, specifically. “ALPHA-003 was under development as a new form of anti-inflammatory drug that worked by blocking the activating effects of the key inflammatory ligand, hGIIA, on a range of cell structural proteins,” Professor Graham Kelly, Filamon’s co-founder, CEO, and Managing Director said in an interview with . “Activation of those proteins underlies most chronic inflammatory changes. Recent published data has shown that tau is another structural protein that responds to hGIIA, so we simply asked the question whether ALPHA-003 would have the same protective effect on tau. Our studies showed that it does, to the extent of blocking the ability of tau to form sheets of oligomers that comprise the ‘tau neurofibrillary tangles.’” But it wasn’t just the need to fill a treatment niche that drove the drug’s development. Kelly explained to that experiencing the devastating effects of dementia first-hand was also a motivating factor. “The personal angle has been the confronting experience of seeing a very good friend who has always been a bundle of energy and force of nature deteriorate into a tragic, sunken, shell of a woman who has lost all recognition of friends and family,” he said. But does ALPHA-003 work? Pre-clinical studies strongly suggest that it does. Importantly, the drug has been found to cross the blood-brain barrier in mammals, meaning it can exert a direct effect on brain cells. The team at Filamon were so happy with the results that they announced them prior to journal publication. “The announced news is literally freshly generated,” Kelly told . “We considered it to be of such importance to warrant being released pre-publication. More studies are underway, and the results of those studies will be the subject of journal submissions.” Kelly foresees ALPHA-003 being used to treat dementia at the time of diagnosis. “We see dementia as a two-step process involving (i) creation of an ongoing neuroinflammatory trigger, and (ii) the consequences of that trigger,” he told . “ALPHA-003 is aiming at blocking the latter, but that requires accepting that the underlying neuroinflammation trigger continues unabated. ALPHA-003 simply is aiming to mitigate the effects of the trigger. Another Filamon experimental drug program underway with another drug technology aims to deactivate this trigger.” Filamon aims to have ALPHA-003 available for use in 2026. It’s expected that the drug will treat tauopathies other than the two major forms of dementia – Alzheimer’s disease and frontotemporal dementia – such as progressive supranuclear palsy, an uncommon Parkinson’s-like disorder, and CTE, caused by repeated concussions. Source: [PDF]

Mbappe, Vinicius and Bellingham on target as Real Madrid beats Atalanta 3-2. Liverpool wins again

Real Madrid’s big stars turned on the style to revive the Spanish giant’s faltering Champions League title defense on Tuesday. Galacticos Kylian Mbappe, Vinicius Junior and Jude Bellingham all scored in a thrilling 3-2 win at Italian league leader Atalanta. But Madrid still had to ride its luck as Mateo Retegui fired over from in front of goal in stoppage time when handed a golden chance to level the game. It was only Madrid’s third win in the competition’s revamped league phase and leaves the 15-time champion in the unseeded playoff positions in 18th place. “It’s a very important win. Not everyone wins here. We suffered and competed. In the Champions League, you have to suffer,” Madrid coach Carlo Ancelotti said. “It’s still difficult to finish in the top eight, but we have two games left to earn points.” Six-time champion Liverpool leads the way after maintaining its perfect record in Europe this season with a 1-0 win against Girona. Like Madrid, Paris Saint-Germain also picked up a much-needed win, beating Salzburg 3-0 to sit in the last playoff spot in 24th place. Bayer Leverkusen is second after a 1-0 win over Inter Milan, while Aston Villa beat Leipzig 3-2 and is third. The top eight teams advance directly to the round of 16. Positions nine to 24 face a playoff to reach the next phase. After three losses in its opening five games of the league phase, the pressure was mounting on Madrid. Questions were also being asked of Mbappe after his uncertain start since his offseason move from PSG. But he produced a moment of class to fire Madrid 1-0 up after 10 minutes at Gewiss Stadium — controlling the ball with his left foot and then finishing low with his right. It was the 25-year-old Mbappe's 50th Champions League goal . Lionel Messi is the only player to have reached that number at a younger age. Mbappe was substituted off before halftime with an apparent physical issue and Charles De Ketelaere leveled the game before the break from the penalty spot. But two goals inside three second-half minutes from Vinicius Junior and Bellingham put Madrid in control. Ademola Lookman's goal made it 3-2, but Madrid survived Retegui's late effort and held on. Mohamed Salah’s 50th Champions League goal maintained Liverpool’s perfect record in the competition this season. The Egypt forward struck a 63rd minute penalty to seal the win in Spain that kept Liverpool atop the 36-team league. But even after a sixth straight win for the Merseyside club, head coach Arne Slot was critical of his players in a game that saw goalkeeper Alisson pull off several saves to keep Girona out. “If you ask me about all the six games, I’m really pleased with all the results, I am really pleased with the five (other) games with the way we played. I’m far from pleased about the performance tonight,” he said. Salah’s goal was his 16th in 22 appearances overall this season. Girona was 30th with just one win from six games. “I almost feel sorry for them because they deserved so much more in this Champions League campaign than the three points they have until now. But we have an incredible goalkeeper,” said Slot, whose team also leads the Premier League. Liverpool’s two remaining games are against Lille at home and PSV Eindhoven away in January. U.S. international Christian Pulisic is the only player to have scored against Liverpool in this season’s Champions League in a 3-1 loss for Milan in September. Bayern Munich routed Shakhtar Donetsk 5-1 to move into the automatic qualifying positions for the round of 16. Michael Olise scored a wonderful solo goal by dribbling past a host of players for his first of two in the game. Bayern's win came after going 1-0 down inside five minutes to a goal from Brazilian winger Kevin. PSG is not done yet. A miserable start to the league phase saw the French giant pick up just four points from five games as it adjusted tp life without stars like Mbappe, Messi and Neymar, who have all departed in the past two seasons. But victory at Salzburg moved PSG up into the playoff positions. Goncalo Ramos, Nuno Mendes and Desire Doue all scored. Leverkusen is back on a roll after struggling to repeat the success of last season's stunning German league and cup double. It's now six straight wins in all competitions, with Nordi Mukiele's 90th minute goal securing victory against Inter and moving Leverkusen into second on 13 points — five behind Liverpool. Villa, Inter and Brest are all on 13 points as well. Inter dropped to fourth after conceding for the first time in this season's competition. Villa is third after its own resurgence in form. Victory against Leipzig was its third in a row after an eight-game winless run. Brest is one of this season’s surprise packages on its Champions League debut and is fifth after beating PSV Eindhoven 1-0. Sporting Lisbon, in 12th, couldn’t build on taking a third-minute lead at Club Brugge — losing 2-1 in Belgium. Brugge is 14th. Dinamo Zagreb drew 0-0 with Celtic and both teams remain in the playoff positions. James Robson is at https://twitter.com/jamesalanrobson AP soccer: https://apnews.com/hub/soccer